2. Anti-infection Metabolic Enzyme/Protease
  3. Bacterial Aminoacyl-tRNA Synthetase
  4. Epetraborole

Epetraborole  (Synonyms: GSK-2251052; AN 3365)

目录号: HY-12479
产品使用指南

摩尔计算器

Epetraborole (GSK2251052) 是一种亮氨酰-tRNA 合成酶 (LeuRS) 抑制剂 (IC50=0.31 μM)，从而抑制蛋白质的合成。Epetraborole 可用于耐多药的革兰氏阴性病原体感染的研究。

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Epetraborole Chemical Structure

Epetraborole Chemical Structure

CAS No. : 1093643-37-8

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Epetraborole 的其他形式现货产品:

Customer Review

Other Forms of Epetraborole:

Epetraborole 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Epetraborole (GSK2251052) is a leucyl-tRNA synthetase (LeuRS) inhibitor (IC50=0.31 μM), thereby inhibiting protein synthesis. Epetraborole can be used in multidrug-resistant gram-negative pathogens infection research[1][2][3].

IC50 & Target

IC50: 0.31 μM (LeuRS)[3]
体外研究
(In Vitro)

Epetraborole (0-32 μg/mL) shows anti-bacterial activity against key gram-negative aerobic and anaerobic pathogens and gram-positive anaerobes[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Epetraborole 相关抗体:

Cell Viability Assay[1]

Cell Line: Anaerobes isolates
Concentration: 0-32 μg/mL
Incubation Time:
Result: Showed MIC50/MIC90 for all anaerobes isolates tested of 2 and 4 μg/mL, respectively.
分子量

237.06

Formula

C11H16BNO4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Epetraborole 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Epetraborole1093643-37-8GSK-2251052 AN 3365GSK2251052GSK 2251052AN3365AN 3365AN-3365BacterialAminoacyl-tRNA SynthetasetRNA Synthetase, aaRSmultidrug-resistant gram-negative pathogens infectionanaerobes isolatesInhibitorinhibitorinhibit

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