1. Anti-infection
  2. Bacterial
  3. Ergosterol peroxide

Ergosterol peroxide  (Synonyms: 过氧麦角甾醇)

目录号: HY-N3845 纯度: ≥98.0%
COA 产品使用指南

Ergosterol peroxide 是一种类固醇衍生物,可以从各种真菌、酵母、地衣或海绵中分离出来。Ergosterol peroxide 具有抗肿瘤、促凋亡、抗炎、抗分枝杆菌和抗增殖活性。

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Ergosterol peroxide Chemical Structure

Ergosterol peroxide Chemical Structure

CAS No. : 2061-64-5

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规格 价格 是否有货 数量
1 mg ¥1300
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10 mg   询价  

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ergosterol peroxide is a steroid derivative and can be isolated from a variety of fungi, yeast, lichens or sponges. Ergosterol peroxide has anti-tumour, proapoptotic, anti-inflammatory, anti-mycobacterial, and anti-proliferative activities[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
B16 IC50
77.9 μM
Compound: 6
Cytotoxicity against murine B16 cells by MTT assay
Cytotoxicity against murine B16 cells by MTT assay
[PMID: 17256903]
BV-2 IC50
6.3 μM
Compound: 22
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced iNOS-dependent nitrite production after 24 hrs by Griess method
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced iNOS-dependent nitrite production after 24 hrs by Griess method
[PMID: 21028898]
HEK293 EC50
0.85 μM
Compound: 2
Agonist activity at full length mouse FXR/RXRalpha expressed in human HEK293 cells assessed as induction of transcriptional activity after 18 hrs by dual luciferase reporter gene assay
Agonist activity at full length mouse FXR/RXRalpha expressed in human HEK293 cells assessed as induction of transcriptional activity after 18 hrs by dual luciferase reporter gene assay
[PMID: 22014750]
KB ED50
9.79 μg/mL
Compound: 4
Cytotoxicity against human KB cells after 4 days
Cytotoxicity against human KB cells after 4 days
[PMID: 1791484]
PLC-PRF-5 ED50
10.99 μg/mL
Compound: 4
Cytotoxicity against human PLC/PRF/5 cells after 4 days
Cytotoxicity against human PLC/PRF/5 cells after 4 days
[PMID: 1791484]
RAW264.7 IC50
9.4 μM
Compound: 9
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production by Griess reaction method
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production by Griess reaction method
[PMID: 23357630]
分子量

428.65

Formula

C28H44O3

CAS 号
性状

固体

颜色

White to off-white

中文名称

过氧麦角甾醇

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

溶解性数据
细胞实验: 

DMSO 中的溶解度 : 11.11 mg/mL (25.92 mM; 超声加热助溶; 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.3329 mL 11.6645 mL 23.3291 mL
5 mM 0.4666 mL 2.3329 mL 4.6658 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: ≥98.0%

参考文献

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3329 mL 11.6645 mL 23.3291 mL 58.3226 mL
5 mM 0.4666 mL 2.3329 mL 4.6658 mL 11.6645 mL
10 mM 0.2333 mL 1.1665 mL 2.3329 mL 5.8323 mL
15 mM 0.1555 mL 0.7776 mL 1.5553 mL 3.8882 mL
20 mM 0.1166 mL 0.5832 mL 1.1665 mL 2.9161 mL
25 mM 0.0933 mL 0.4666 mL 0.9332 mL 2.3329 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Ergosterol peroxide
目录号:
HY-N3845
需求量: