2. Vitamin D Related/Nuclear Receptor
  3. Estrogen Receptor/ERR
  4. ERRγ inverse agonist 2

ERRγ inverse agonist 2 (compound 19) 是一种有效的选择性 ERRγ 反向激动剂，Kd 值为 6.5 μM。ERRγ inverse agonist 2 抑制铁调素、纤维蛋白原和糖异生基因的表达。ERRγ inverse agonist 2 具有抗菌、抗凝血和抗糖尿病活性。

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ERRγ inverse agonist 2 Chemical Structure

ERRγ inverse agonist 2 Chemical Structure

CAS No. : 324022-01-7

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ERRγ inverse agonist 2 相关抗体

Top Publications Citing Use of Products

查看 Estrogen Receptor/ERR 亚型特异性产品:

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Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ERRγ inverse agonist 2 (compound 19) is a potent and selective ERRγ inverse agonist with a Kd value of 6.5 μM. ERRγ inverse agonist 2 inhibits the expression of hepcidin, fibrinogen and gluconeogenic genes. ERRγ inverse agonist 2 has antimicrobial, anti-coagulant and antidiabetic activities[1].

IC50 & Target[1].

ERRγ

6.5 μM (Kd)

体外研究
(In Vitro)

ERRγ inverse agonist 2 (1-10 μM; 293T 细胞) 抑制 ERRγ 的 PGC-1α 依赖性转录活性，对 ERRα 和 ERRβ 的抑制作用微弱[1]。
ERRγ inverse agonist 2 (10 μM; AML12 细胞) 抑制铁调素、纤维蛋白原和糖异生基因的表达[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

ERRγ inverse agonist 2 相关抗体:
分子量

447.49

Formula

C27H21N5O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

ERRγ inverse agonist 2 相关分类

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Keywords:

ERRγ inverse agonist 2324022-01-7ERRγ inverse agonist2ERRγ inverse agonist-2Estrogen Receptor/ERRhepcidinfibrinogengluconeogenic genesantimicrobialanti-coagulantantidiabeticInhibitorinhibitorinhibit

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