2. Vitamin D Related/Nuclear Receptor
  3. Estrogen Receptor/ERR
  4. Estrogen receptor α antagonist 1

Estrogen receptor α antagonist 1 

目录号: HY-150692
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摩尔计算器

Estrogen receptor α antagonist 1 (compound 35) 是 estrogen receptor α 的高选择性拮抗剂，对 estrogen receptor α，estrogen receptor β 和 MCF-7细胞 的 IC50 值分别为 0.02、6.55 和 7.73 μM。Estrogen receptor α antagonist 1 可用于肿瘤的研究。

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Estrogen receptor α antagonist 1 Chemical Structure

Estrogen receptor α antagonist 1 Chemical Structure

CAS No. : 2580941-45-1

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Estrogen receptor α antagonist 1 相关抗体

Top Publications Citing Use of Products

查看 Estrogen Receptor/ERR 亚型特异性产品:

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Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Estrogen receptor α antagonist 1 (compound 35) is a highly selective antagonist of estrogen receptor α, with IC50s of 0.02, 6.55 and 7.73 μM for estrogen receptor α, estrogen receptor β and MCF-7 cells, respectively. Estrogen receptor α antagonist 1 can be used for the research of cancer[1].

IC50 & Target

IC50: 0.02 μM (estrogen receptor α), 6.55 μM (estrogen receptor β), 7.73 μM (MCF-7 cells)[1]
体外研究
(In Vitro)

Estrogen receptor α antagonist 1 (compound 35) (1 nM-100 μM; 72 h) selectively inhibits estrogen receptor α, estrogen receptor β and MCF-7 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Estrogen receptor α antagonist 1 相关抗体:

Cell Viability Assay[1]

Cell Line: MCF-7 cells
Concentration: 1 nM-100 μM
Incubation Time: 72 hours
Result: Exhibited IC50s of 0.02, 6.55 and 7.73 μM for estrogen receptor α, estrogen receptor β and MCF-7 cells, respectively at 72 hours.
分子量

452.54

Formula

C26H32N2O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Estrogen receptor α antagonist 1 相关分类

  • 摩尔计算器

  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Estrogen receptor α antagonist 12580941-45-1Estrogen receptor α antagonist1Estrogen receptor α antagonist-1Estrogen Receptor/ERRisoform selectivitysubtype selectivitybenzopyrananticanceranti-proliferativeInhibitorinhibitorinhibit

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