2. Vitamin D Related/Nuclear Receptor
  3. Estrogen Receptor/ERR
  4. Estrogen receptor α antagonist 1

Estrogen receptor α antagonist 1 

目录号: HY-150692
产品使用指南

摩尔计算器

Estrogen receptor α antagonist 1 (compound 35) 是 estrogen receptor α 的高选择性拮抗剂，对 estrogen receptor α，estrogen receptor β 和 MCF-7细胞 的 IC50 值分别为 0.02、6.55 和 7.73 μM。Estrogen receptor α antagonist 1 可用于肿瘤的研究。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Estrogen receptor α antagonist 1 Chemical Structure

Estrogen receptor α antagonist 1 Chemical Structure

CAS No. : 2580941-45-1

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

Estrogen receptor α antagonist 1 相关抗体

Top Publications Citing Use of Products

查看 Estrogen Receptor/ERR 亚型特异性产品:

查看所有亚型
Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Estrogen receptor α antagonist 1 (compound 35) is a highly selective antagonist of estrogen receptor α, with IC50s of 0.02, 6.55 and 7.73 μM for estrogen receptor α, estrogen receptor β and MCF-7 cells, respectively. Estrogen receptor α antagonist 1 can be used for the research of cancer[1].

IC50 & Target

IC50: 0.02 μM (estrogen receptor α), 6.55 μM (estrogen receptor β), 7.73 μM (MCF-7 cells)[1]
细胞效力
(Cellular Effect)
Cell Line Type Value Description References
MCF7 IC50
7.73 μM
Compound: 35
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell viability after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell viability after 72 hrs by MTT assay
[PMID: 31987694]
体外研究
(In Vitro)

Estrogen receptor α antagonist 1 (compound 35) (1 nM-100 μM; 72 h) selectively inhibits estrogen receptor α, estrogen receptor β and MCF-7 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Estrogen receptor α antagonist 1 相关抗体:

Cell Viability Assay[1]

Cell Line: MCF-7 cells
Concentration: 1 nM-100 μM
Incubation Time: 72 hours
Result: Exhibited IC50s of 0.02, 6.55 and 7.73 μM for estrogen receptor α, estrogen receptor β and MCF-7 cells, respectively at 72 hours.
分子量

452.54

Formula

C26H32N2O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Estrogen receptor α antagonist 1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Estrogen receptor α antagonist 12580941-45-1Estrogen receptor α antagonist1Estrogen receptor α antagonist-1Estrogen Receptor/ERRisoform selectivitysubtype selectivitybenzopyrananticanceranti-proliferativeInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Estrogen receptor α antagonist 1
目录号：
HY-150692
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z