2. MAPK/ERK Pathway
  3. MNK
  4. ETC-168

ETC-168 是一种选择性的口服有效的 MNK 抑制剂，对 MNK1 和 MNK2 的IC50 值分别为 23 nM 和 43 nM。ETC-168 在体内和体外均有抗增殖作用。

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ETC-168 Chemical Structure

ETC-168 Chemical Structure

CAS No. : 1464150-99-9

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ETC-168 相关抗体

Top Publications Citing Use of Products

查看 MNK 亚型特异性产品:

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MNK1 MNK2 MNK

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ETC-168 is a selective and oral active MNK inhibitor with the IC50 values of 23 and 43 nM against MNK1 and MNK2, respectively. ETC-168 shows antiproliferative efficacy in vivo and in vitro[1].

IC50 & Target

MNK1

23 nM (IC50)

MNK2

43 nM (IC50)

分子量

409.44

Formula

C24H19N5O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

ETC-168 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ETC-1681464150-99-9ETC168ETC 168MNKMitogen activated protein kinase interacting kinaseMAP kinase interacting kinaseMAPK interacting kinaseSoft tissue sarcomaSTS cellantiproliferative efficacyInhibitorinhibitorinhibit

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产品名称：
ETC-168
目录号：
HY-156511
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