2. NF-κB Metabolic Enzyme/Protease Membrane Transporter/Ion Channel Neuronal Signaling
  3. NF-κB Glutathione S-transferase Calcium Channel
  4. Ethacrynic acid sodium

Ethacrynic acid sodium  (Synonyms: 依他尼酸钠; Etacrynic acid sodium; Sodium etacrynate)

目录号: HY-B1640A
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摩尔计算器

Ethacrynic acid (Etacrynic acid sodium) sodium 是一种利尿剂。Ethacrynic acid sodium 是谷胱甘肽 S-转移酶 (GSTs) 的抑制剂。Ethacrynic acid sodium 是一种 NF-κB 信号传导途径的有效抑制剂，并且还调节白三烯的形成。Ethacrynic acid sodium 还可抑制 L 型电压依赖性和储存操作的钙通道，从而导致气道平滑肌细胞松弛。Ethacrynic acid sodium 具有抗炎特性，可减轻类维生素 A 诱导的小鼠耳部水肿。

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Ethacrynic acid sodium Chemical Structure

Ethacrynic acid sodium Chemical Structure

CAS No. : 6500-81-8

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Ethacrynic acid sodium 的其他形式现货产品:

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Ethacrynic acid sodium 相关抗体

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生物活性

Ethacrynic acid (Etacrynic acid sodium) sodium is a diuretic. Ethacrynic acid sodium is an inhibitor of glutathione S-transferases (GSTs). Ethacrynic acid sodium is a potent inhibitor of NF-kB-signaling pathway, and also modulates leukotriene formation. Ethacrynic acid sodium also inhibits L-type voltage-dependent and store-operated calcium channel, leading to relaxation of airway smooth muscle (ASM) cells. Ethacrynic acid sodium has anti-inflammatory properties that reduces the retinoid-induced ear edema in mice[1][2][3][4].

Clinical Trial
分子量

325.12

Formula

C13H11Cl2NaO4
CAS 号
中文名称

依他尼酸钠
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Ethacrynic acid sodium 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ethacrynic acid6500-81-8Etacrynic acid Sodium etacrynate依他尼酸钠NF-κBGlutathione S-transferaseCalcium ChannelNuclear factor-κBNuclear factor-kappaBGlutathione transferasesGSTsCa2+ channelsCa channelsInhibitorinhibitorinhibit

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