2. Antibody-drug Conjugate/ADC Related Cell Cycle/DNA Damage
  3. ADC Cytotoxin Topoisomerase
  4. Exatecan-amide-bicyclo[1.1.1]pentan-1-ol

Exatecan-amide-bicyclo[1.1.1]pentan-1-ol 

目录号: HY-160597
产品使用指南

摩尔计算器

Exatecan-amide-bicyclo[1.1.1]pentan-1-ol (Compound 79) 是 exatecan (HY-13631) 衍生物，可用作药物缀合物的有效负载。Exatecan-amide-bicyclo[1.1.1]pentan-1-ol 对多种肿瘤细胞系具有显著的抑制活性。

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Exatecan-amide-bicyclo[1.1.1]pentan-1-ol Chemical Structure

Exatecan-amide-bicyclo[1.1.1]pentan-1-ol Chemical Structure

CAS No. : 2866299-06-9

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Exatecan-amide-bicyclo[1.1.1]pentan-1-ol 相关抗体

Top Publications Citing Use of Products

查看 ADC Cytotoxin 亚型特异性产品:

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Auristatin Calicheamicins Camptothecins Daunorubicins/Doxorubicins Duocarmycins Maytansinoids Pyrrolobenzodiazepines Traditional Cytotoxic Agents

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Topoisomerase Topo I Topo II

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Exatecan-amide-bicyclo[1.1.1]pentan-1-ol (Compound 79) is an exatecan (HY-13631) derivative that can be used as a payload in drug conjugates. Exatecan-amide-bicyclo[1.1.1]pentan-1-ol has significant inhibitory activity against a variety of tumor cell lines[1].

IC50 & Target

Camptothecins

 

分子量

545.56

Formula

C30H28FN3O6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Exatecan-amide-bicyclo[1.1.1]pentan-1-ol 相关分类

  • 摩尔计算器

  • 稀释计算器

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Exatecan-amide-bicyclo[1.1.1]pentan-1-ol2866299-06-9ADC CytotoxinTopoisomeraseADC Payloadtumor cellpayloaddrug conjugatesInhibitorinhibitorinhibit

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