1. GPCR/G Protein
  2. GLP Receptor
  3. Exendin-P5

Exendin-P5 是一种选择性靶向 GLP-1R 的激动剂。Exendin-P5 通过与 GLP-1R 跨膜域的瞬时相互作用促进 G 蛋白的快速激活,从而提高其在 G 蛋白介导的信号传导中的效能,加快 cAMP 产生。这种机制使得 Exendin-P5 在代谢疾病的研究中具有潜在的应用价值。

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Exendin-P5 Chemical Structure

Exendin-P5 Chemical Structure

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     可免费申领三个不同产品的试用装。

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规格 是否有货
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Exendin-P5 is a selective agonist that targets the GLP-1R. Exendin-P5 promotes rapid activation of G proteins by transient interactions with the transmembrane domain of GLP-1R, enhancing its potency in G protein-mediated signaling and accelerating cAMP production. This mechanism suggests the potential application of Exendin-P5 in the study of metabolic diseases[1].

分子量

4209.65

Formula

C185H291N49O61S

Sequence

Glu-Leu-Val-Asp-Asn-Ala-Val-Gly-Gly-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ala

Sequence Shortening

ELVDNAVGGDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPA

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

产品名称:
Exendin-P5
目录号:
HY-P10716
需求量: