2. Apoptosis
  3. Bcl-2 Family
  4. F1324

F1324 是一种有效、高亲和力的 BCL6 多肽抑制剂，IC50 值为 1 nM。F1324 结合 BCL6 的动力学 t1/2 为 441 s ，对 BCL6 PPI 具有很强的抑制作用。

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Custom Peptide Synthesis

F1324 Chemical Structure

F1324 Chemical Structure

CAS No. : 2607975-44-8

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Other Forms of F1324:

F1324 相关抗体

Top Publications Citing Use of Products

查看 Bcl-2 Family 亚型特异性产品:

查看所有亚型
Bcl-2 Bcl-xL Bcl-W Mcl-1 Bfl-1 Bcl-B Bax Bak Bim

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

F1324 is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6) with an IC50 of 1 nM. F1324 exhibits binding t1/2 value of 441 s and has strong inhibition activity against BCL6 PPI[1].

IC50 & Target

IC50: 1 nM (BCL6)[1]
体外研究
(In Vitro)

F1324 binds to BCL6(5-129) with KD and IC50 values of 0.57 nM and 1 nM according to the results of an SPR analysis and cell-free ELISA assay, respectively[1].
F1324 binds BCL6 not only in cell-free but also cellbased conditions[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

F1324 相关抗体:
分子量

1765.04

Formula

C83H121N21O20S
CAS 号
Sequence Shortening

Ac-LWYTDIRMSWRVP-OH
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

F1324 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

F13242607975-44-8F 1324F-1324Bcl-2 FamilyBCL6protein-proteininteractionPPIInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-100866
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