2. Cytoskeleton Cell Cycle/DNA Damage Neuronal Signaling Membrane Transporter/Ion Channel Autophagy Stem Cell/Wnt TGF-beta/Smad Epigenetics Anti-infection
  3. ROCK Calcium Channel Autophagy PKA PKC HIV
  4. Fasudil Hydrochloride (Standard)

Fasudil Hydrochloride (Standard)  (Synonyms: 盐酸法舒地尔(Standard))

目录号: HY-10341R 纯度: ≥98%
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摩尔计算器

Fasudil (Hydrochloride) (Standard)是 Fasudil (Hydrochloride) 的分析标准品。本产品用于研究及分析应用。Fasudil (HA-1077; AT877) Hydrochloride 是一种非特异性 RhoA/ROCK 抑制剂，并抑制蛋白激酶。Fasudil Hydrochloride 抑制 ROCK1 的 Ki 为 0.33 μM，抑制 ROCK2，PKA，PKC，PKG 的 IC50 分别为 0.158 μM 和 4.58 μM，12.30 μM，1.650 μM。Fasudil Hydrochloride 也是一种有效的 Ca2+ 通道拮抗剂和血管扩张剂。

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Fasudil Hydrochloride (Standard) Chemical Structure

Fasudil Hydrochloride (Standard) Chemical Structure

CAS No. : 105628-07-7

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生物活性

Fasudil (Hydrochloride) (Standard) is the analytical standard of Fasudil (Hydrochloride). This product is intended for research and analytical applications. Fasudil (HA-1077; AT877) Hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil Hydrochloride is also a potent Ca2+ channel antagonist and vasodilator.

分子量

327.83

Formula

C14H18ClN3O2S
CAS 号
中文名称

盐酸法舒地尔(Standard)
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Fasudil Hydrochloride (Standard) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fasudil Hydrochloride (Standard)105628-07-7盐酸法舒地尔(Standard)ROCKCalcium ChannelAutophagyPKAPKCHIVRho-associated protein kinaseRho-associated kinaseRho-kinaseROKCa2+ channelsCa channelsProtein kinase AProtein kinase CHuman immunodeficiency virusorally activeprotein kinasescollagena-SMATIMP-1ERK1/2JNKp38rat HSCshuman HSCTWNT-4 cellsCa2+ channel antagonistvasodilatorlysophoaphatidic acidLPAInhibitorinhibitorinhibit

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