1. Cell Cycle/DNA Damage Anti-infection
  2. DNA/RNA Synthesis Influenza Virus SARS-CoV Bacterial
  3. Favipiravir sodium

Favipiravir sodium  (Synonyms: T-705 sodium)

目录号: HY-14768A
产品使用指南

Favipiravir (T-705) sodium 是一种病毒 RNA 聚合酶 (RNA polymerase) 抑制剂,可转变为其活性形式 Favipiravir-ribofuranosyl-5′-triphosphate (RTP)。Favipiravir-RTP 抑制流感病毒 RNA 依赖性的 RNA 聚合酶 (RdRP) 活性,IC50 为 341 nM。

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Favipiravir sodium Chemical Structure

Favipiravir sodium Chemical Structure

CAS No. : 1366418-99-6

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Favipiravir sodium 的其他形式现货产品:

Other Forms of Favipiravir sodium:

MCE 顾客使用本产品发表的 40 篇科研文献

IF

    Favipiravir sodium purchased from MCE. Usage Cited in: BMC Vet Res. 2019 Sep 2;15(1):316.  [Abstract]

    Comparisons of antiviral effects of T-705 and anti-CDV polyclonal serum. The Vero and DH82 cells were treated with T-705 (156.25 μg/ml), anti-CDV polyclonal serum (1:128) and a combination of T-705 (156.25 μg/ml) and anti-CDV polyclonal serum (1:128) at 0, 12, 24, 36 and 48 h p.i. with CDV-3 and CDV-11 at a MOI of 0.1. The mock groups were treated with DMEM p.i. at the same times. The virus titers in supernatant (b, d, f, h) were determined and compared with the viral titers in mock group. All e

    Favipiravir sodium purchased from MCE. Usage Cited in: BMC Vet Res. 2019 Sep 2;15(1):316.  [Abstract]

    Comparisons of antiviral effects of T-705 and anti-CDV polyclonal serum. The Vero and DH82 cells were treated with T-705 (156.25 μg/ml), anti-CDV polyclonal serum (1:128) and a combination of T-705 (156.25 μg/ml) and anti-CDV polyclonal serum (1:128) at 0, 12, 24, 36 and 48 h p.i. with CDV-3 and CDV-11 at a MOI of 0.1. The mock groups were treated with DMEM p.i. at the same times. Viral replications in cells were detected by IFA and the mean fluorescence percentages (a, c, e, g) were calculated
    • 生物活性

    • 纯度 & 产品资料

    • 参考文献

    生物活性

    Favipiravir (T-705) sodium is an inhibitor of viral RNA polymerase (RNA polymerase), which is converted into its active form Favipiravir-ribofuranosyl-5′-triphosphate (RTP). Favipiravir-RTP inhibits the activity of influenza virus RNA-dependent RNA polymerase (RdRP) with an IC50 of 341 nM[1][2].

    分子量

    179.08

    Formula

    C5H3FN3NaO2

    CAS 号
    运输条件

    Room temperature in continental US; may vary elsewhere.

    储存方式

    Please store the product under the recommended conditions in the Certificate of Analysis.

    纯度 & 产品资料
    参考文献
    • 摩尔计算器

    • 稀释计算器

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    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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