2. GPCR/G Protein
  3. Free Fatty Acid Receptor
  4. FFA2 agonist-1

FFA2 agonist-1 (Compound 4) 是游离脂肪酸受体 2 (FFA2/GPR43) 的激动剂，EC50 为 81 nM。FFA2 agonist-1 在 β-arrestin-2 募集试验和 cAMP 抑制试验中表现出活性，EC50 分别为 1.2 μM 和 0.53 μM。FFA2 agonist-1 可引发食欲调节肽 YY (PYY) 粘膜反应，抑制脂肪堆积、肠道功能和食物摄入，可用于肥胖研究。

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FFA2 agonist-1 Chemical Structure

FFA2 agonist-1 Chemical Structure

CAS No. : 1312799-06-6

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FFA2 agonist-1 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

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生物活性

FFA2 agonist-1 (Compound 4) is the agonist for Free fatty acid receptor 2 (FFA2/GPR43) with an EC50 of 81 nM. FFA2 agonist-1 exhibits activity in β-arrestin-2 recruitment assay and cAMP inhibition assay with EC50 of 1.2 μM and 0.53 μM. FFA2 agonist-1 leads to appetite regulating peptide YY (PYY) mucosal responses, inhibits the fat accumulation, intestinal functions and food intake, and can be used for obesity research[1].

IC50 & Target

EC50: 81 nM (FFA2/GPR43)
分子量

435.90

Formula

C25H22ClNO4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

FFA2 agonist-1 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

FFA2 agonist-11312799-06-6Free Fatty Acid ReceptorFFARobesityPPYappetite regulatingInhibitorinhibitorinhibit

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