1. Protein Tyrosine Kinase/RTK
  2. DYRK
  3. FINDY

FINDY 是 DYRK1A 的折叠中间选择性抑制剂。FINDY 可以抑制 Ser97 自身磷酸化,IC50 值为 35 μM。FINDY 可用于神经障碍的研究。

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FINDY Chemical Structure

FINDY Chemical Structure

CAS No. : 1507367-37-4

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规格 价格 是否有货 数量
25 mg ¥10022
3 - 4 周
50 mg   询价  
100 mg   询价  

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Customer Review

查看 DYRK 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

FINDY is a folding intermediate-selective inhibitor of DYRK1A. FINDY can inhibit Ser97 autophosphorylation with an IC50 value of 35 μM. FINDY can be used for the research of neurological disorder[1]. FINDY is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC50 & Target

IC50: 35 μM (Ser97 autophosphorylation)[1]

体外研究
(In Vitro)

FINDY (Compound 1) inhibits Ser97 autophosphorylation with an IC50 value of 35 μM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

347.53

Formula

C16H17NO2S2Si

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
FINDY
目录号:
HY-152183
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