2. GPCR/G Protein Neuronal Signaling Anti-infection Membrane Transporter/Ion Channel
  3. Dopamine Receptor SARS-CoV Sodium Channel
  4. Fluphenazine (dihydrochloride) (Standard)

Fluphenazine (dihydrochloride) (Standard)  (Synonyms: 盐酸氟奋乃静 (标准品))

目录号: HY-A0081R 纯度: ≥98%
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Fluphenazine (dihydrochloride) (Standard) 是 Fluphenazine (dihydrochloride) 的分析标准品。本产品用于研究及分析应用。 Fluphenazine dihydrochloride 是一种有效且具有口服活性的吩噻嗪类多巴胺受体 (dopamine receptor) 拮抗剂。Fluphenazine dihydrochloride 阻断神经元电压门控的钠离子通道 (sodium channels)。Fluphenazine dihydrochloride 主要通过拮抗中边缘、黑质纹状体和下颌结节神经通路的突触后多巴胺-2 受体来发挥作用。Fluphenazine dihydrochloride 可拮抗苯甲酸甲酯诱导的小鼠刻板咬伤，抑制小鼠攀爬行为。Fluphenazine dihydrochloride 可用于研究精神病以及与糖尿病相关的疼痛性周围神经病变，并有抑制 SARS-CoV-2 的潜力。

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Fluphenazine (dihydrochloride) (Standard) Chemical Structure

Fluphenazine (dihydrochloride) (Standard) Chemical Structure

CAS No. : 146-56-5

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生物活性

Fluphenazine (dihydrochloride) (Standard) is the analytical standard of Fluphenazine (dihydrochloride). This product is intended for research and analytical applications. Fluphenazine dihydrochloride is a potent, orally active phenothiazine-based dopamine receptor antagonist. Fluphenazine dihydrochloride blocks neuronal voltage-gated sodium channels. Fluphenazine dihydrochloride acts primarily through antagonism of postsynaptic dopamine-2 receptors in mesolimbic, nigrostriatal, and tuberoinfundibular neural pathways. Fluphenazine dihydrochloride can antagonize Methylphenidate-induced stereotyped gnawing and inhibit climbing behaviour in mice. Fluphenazine dihydrochloride can be used for researching psychosis and painful peripheral neuropathy associated with diabetes and has potential to inhibit SARS-CoV-2.

分子量

510.44

Formula

C22H28Cl2F3N3OS
CAS 号
中文名称

盐酸氟奋乃静 (标准品)
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Fluphenazine (dihydrochloride) (Standard) 相关分类

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fluphenazine (dihydrochloride) (Standard)146-56-5盐酸氟奋乃静 (标准品)Dopamine ReceptorSARS-CoVSodium ChannelSARS coronavirusNa channelsNa+ channelsInhibitorinhibitorinhibit

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