2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. DNA/RNA Synthesis Endogenous Metabolite
  4. Folic acid sodium

Folic acid sodium  (Synonyms: Vitamin B9 sodium; Vitamin M sodium)

目录号: HY-16637A
产品使用指南

摩尔计算器

Folic acid (Vitamin B9) sodium 是一种来自维生素 B 群的口服活性必需营养素。Folic acid sodium 具有抗抑郁样作用。Folic acid sodium 可降低新生儿神经管缺陷的风险。Folic acid sodium 可用于研究因叶酸缺乏引起的巨幼红细胞性贫血和大红细胞性贫血。

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Folic acid sodium Chemical Structure

Folic acid sodium Chemical Structure

CAS No. : 6484-89-5

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规格 是否有货
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100 mg   询价  
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Folic acid sodium 的其他形式现货产品:

Customer Review

Other Forms of Folic acid sodium:

Folic acid sodium 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Folic acid (Vitamin B9) sodium is a orally active essential nutrient from the B complex group of vitamins. Folic acid sodium shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid sodium can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency[1][2][3][4].

IC50 & Target

Microbial Metabolite

 

Human Endogenous Metabolite

 

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
KB IC50
0.5 μM
Compound: folic acid
Photocytotoxicity against human KB cells overexpressing folate receptor assessed as cell viability incubated for 24 hrs followed by halogen light illumination measured after 20 mins by MTT assay
Photocytotoxicity against human KB cells overexpressing folate receptor assessed as cell viability incubated for 24 hrs followed by halogen light illumination measured after 20 mins by MTT assay
[PMID: 24088087]
体外研究
(In Vitro)

Folic acid sodium plays a critical role in the prevention of chromosome breakage and hypomethylation of DNA[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Folic acid sodium 相关抗体:
体内研究
(In Vivo)

Folic acid sodium (10, 50, 100 mg/kg; p.o.) shows an antidepressant-like effect in this behavioral mouse model[2].
Folic acid sodium (1, 10 nmol/site) shows no psychostimulant effect in mice habituated to the novel environment[2].
Folic acid sodium (1, 5 mg/kg; p.o.) prevents epigenetic modification of hepatic gene expression in the offspring in rats[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 30-40 g swiss mice[2]
Dosage: 10, 50, 100 mg/kg
Administration: Oral administration
Result: Decreased the immobility time in the forced swimming test (FST) (F324=11.21) and produced a significant effect in the immobility time in the tail suspension test (TST) (F3,20=5.71).
Animal Model: 30-40 g swiss mice[2]
Dosage: 1-10 nmol/site
Administration: Intracerebroventrical injection
Result: Decreased the immobility time of mice in the FST (F3,22=12.31) and TST (F3,22=5.50).
Animal Model: Virgin female Wistar rats[3]
Dosage: 1, 5 mg/kg (180 g/kg protein with 1 mg/kg folic acid or 90 g/kg casein with 1, 5 mg/kg folic acid)
Administration: Oral administration
Result: Prevented epigenetic modification of hepatic gene expression in the offspring.
Clinical Trial
分子量

464.39

Formula

C19H19N7NaO6
CAS 号
中文名称

叶酸钠
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
溶解性数据
细胞实验： 

H2O 中的溶解度 : 100 mg/mL (215.34 mM; 超声助溶)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.1534 mL 10.7668 mL 21.5336 mL
5 mM 0.4307 mL 2.1534 mL 4.3067 mL
查看完整储备液配制表

* 备注：如您选择水作为储备液，请稀释至工作液后，再用 0.22 μm 的滤膜过滤除菌后使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
该产品水溶性佳，请具体参考实测 水 / PBS / Saline 中的溶解度数据。
您所需的储备液浓度超过该产品的实测溶解度，如有需要，请与 MCE 中国技术支持联系。
纯度 & 产品资料
参考文献

Folic acid sodium 相关分类

完整储备液配制表

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.1534 mL 10.7668 mL 21.5336 mL 53.8341 mL
5 mM 0.4307 mL 2.1534 mL 4.3067 mL 10.7668 mL
10 mM 0.2153 mL 1.0767 mL 2.1534 mL 5.3834 mL
15 mM 0.1436 mL 0.7178 mL 1.4356 mL 3.5889 mL
20 mM 0.1077 mL 0.5383 mL 1.0767 mL 2.6917 mL
25 mM 0.0861 mL 0.4307 mL 0.8613 mL 2.1534 mL
30 mM 0.0718 mL 0.3589 mL 0.7178 mL 1.7945 mL
40 mM 0.0538 mL 0.2692 mL 0.5383 mL 1.3459 mL
50 mM 0.0431 mL 0.2153 mL 0.4307 mL 1.0767 mL
60 mM 0.0359 mL 0.1794 mL 0.3589 mL 0.8972 mL
80 mM 0.0269 mL 0.1346 mL 0.2692 mL 0.6729 mL
100 mM 0.0215 mL 0.1077 mL 0.2153 mL 0.5383 mL

* 备注：如您选择水作为储备液，请稀释至工作液后，再用 0.22 μm 的滤膜过滤除菌后使用。

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Folic acid6484-89-5Vitamin B9Vitamin M叶酸钠Vitamin B 9Vitamin B-9DNA/RNA SynthesisEndogenous Metabolitenutrientntidepressant-likeneural tube defectsfolic deficiencyInhibitorinhibitorinhibit

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