2. Inhibitory Antibodies
  3. Frunevetmab

Frunevetmab  (Synonyms: 夫卢维单抗; NV-02)

目录号: HY-P99627 纯度: ≥95.0%
COA

摩尔计算器

Frunevetmab (NV-02) 是一种猫源化抗神经生长因子 (NGF) 单克隆抗体，Kd 为 20 pM。Frunevetmab 可有效减轻猫的骨关节炎 (OA) 疼痛。

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CAS No. : 1708936-80-4

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规格 价格 是否有货 数量
1 mg ￥4000
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Frunevetmab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Frunevetmab (NV-02) is a felinized anti-nerve growth factor (NGF) monoclonal antibody with a Kd of 20 pM. Frunevetmab can effectively decrease osteoarthritis (OA) pain in cats[1][2].

同型

Human IgG1 kappa
推荐同型对照抗体
种属

Felinized

IC50 & Target

Kd: 20 pM (NGF)[2]
体外研究
(In Vitro)

Frunevetmab (NV-02) 以高亲和力和效力中和 NGF，并且不结合补体[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Frunevetmab 相关抗体:
体内研究
(In Vivo)

Frunevetmab (1.0-2.8mg/kg；皮下注射；第 0、28 和 56 天) 对患有自然发生的骨关节炎疼痛和相关的行动障碍和残疾的猫显示出积极的处理效果[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Cats with naturally-occurring OA pain and associated mobility impairment and disability[1]
Dosage: 1.0-2.8 mg/kg
Administration: s.c; 3 times at 28-day intervals; on days 0, 28, and 56
Result: Reliefed the pain from osteoarthritis in cats.
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

夫卢维单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • IgG1-kappa
纯度 & 产品资料

纯度: ≥95.0%

COA (172 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Frunevetmab 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

Frunevetmab1708936-80-4NV-02夫卢维单抗NV02NV 02OthersanalgesicNGFosteoarthritiscatInhibitorinhibitorinhibit

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