2. 天然产物
  3. 微生物 酮、醛、酸
  4. Ganoderic acid SZ

Ganoderic acid SZ是一种天然产物，具有3-羟基-3-甲基戊二酰辅酶A还原酶抑制活性。Ganoderic acid SZ在抑制HMG-CoA还原酶方面显示出比阳性对照阿托伐他汀更强的活性。Ganoderic acid SZ对酵母来源的α-糖苷酶表现出显著的抑制作用，其IC50值在很低的浓度下即可实现。Ganoderic acid SZ还表现出针对K562细胞的细胞毒性，IC??值在10-20 μM范围内。

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Ganoderic acid SZ Chemical Structure

Ganoderic acid SZ Chemical Structure

CAS No. : 865543-37-9

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Ganoderic acid SZ 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ganoderic acid SZ is a natural product with 3-hydroxy-3-methylglutaryl-CoA reductase inhibitory activity. Ganoderic acid SZ shows stronger activity than the positive control atorvastatin in inhibiting HMG-CoA reductase. Ganoderic acid SZ exhibits significant inhibition of yeast-derived α-glucosidase with IC50 values achieved at very low concentrations. Ganoderic acid SZ also exhibits cytotoxicity against K562 cells with IC?? values in the range of 10-20 μM[1].

分子量

452.67

Formula

C30H44O3
CAS 号
结构分类
初始来源

Ganoderma lucidum
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Ganoderic acid SZ 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ganoderic acid SZ865543-37-9OthersInhibitorinhibitorinhibit

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