1. Gene
  2. Tigit - T cell immunoreceptor with Ig and ITIM domains Gene

Tigit - T cell immunoreceptor with Ig and ITIM domains Gene

种属: Mus musculus

同用名: Vstm3

基因 ID: 100043314 | 基因类型: protein coding

关于 Tigit

功能概要

Enables signaling receptor binding activity. Acts upstream of or within negative regulation of T cell activation. Predicted to be active in cell surface. Orthologous to human TIGIT (T cell immunoreceptor with Ig and ITIM domains). [provided by Alliance of Genome Resources, Apr 2022]

Tigit 基因产物(1)

mRNA Protein Name
NM_001146325.1 NP_001139797.1 T-cell immunoreceptor with Ig and ITIM domains precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
24658051 MGI
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
21416464 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of T cell activation IMP
IMP: 通过突变表型推断
21199897 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

T-cell immunoreceptor with Ig and ITIM domains

V-set and transmembrane domain containing 3

V-set and transmembrane domain-containing protein 3

重组 Tigit 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71009 TIGIT Protein, Mouse (118a.a, HEK293, Fc) NP_001139797 (G26-T143) ≥95%
HY-P72449 TIGIT Protein, Mouse (110a.a, HEK293, His) NP_001139797 (G26-F135) ≥95%
HY-P77235 TIGIT Protein, Mouse (HEK293, mFc) NP_001139797 (A17-G141) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tigit NCBI NCBI:201633
Macaca fascicularis Tigit NCBI NCBI:102121588
Leporidae Tigit NCBI
Rattus norvegicus Tigit NCBI NCBI:363784