2. Gene
  3. Adh5 - alcohol dehydrogenase 5 (class III), chi polypeptide Gene

Adh5 - alcohol dehydrogenase 5 (class III), chi polypeptide Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：乙醇脱氢酶 5 ( II I 类) ，χ 多肽

种属: Rattus norvegicus

基因 ID: 100145871 | 基因类型: protein coding

关于 Adh5

Primary_assembly 2: 226,947,466-226,987,591 forward strand.mRatBN7.2:CM026975.1

This gene has 4 transcripts (splice variants), 404 orthologues, 17 paralogues and is associated with 7 phenotypes. Biased expression in Liver (RPKM 446.4), Kidney (RPKM 263.2) and 9 other tissues.

功能概要

该基因编码的蛋白可启动乙醇脱氢酶 (NAD+) 活性。参与老化和乙醇分解代谢过程。位于细胞质和细胞核中。用于研究酒精使用障碍。胆汁淤积的生物标志物。该基因的人类直系同源物与 AMED 综合征和哮喘有关。与人 ADH5（酒精脱氢酶 5（III 类），chi 多肽）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables alcohol dehydrogenase (NAD+) activity. Involved in aging and ethanol catabolic process. Located in cytoplasm and nucleus. Used to study alcohol use disorder. Biomarker of cholestasis. Human ortholog(s) of this gene implicated in AMED syndrome and asthma. Orthologous to human ADH5 (alcohol dehydrogenase 5 (class III), chi polypeptide). [provided by Alliance of Genome Resources, Apr 2022]

Adh5 基因产物(1)

mRNA Protein Name
NM_001126120.1 NP_001119592.1 alcohol dehydrogenase class-3

Adh5 蛋白结构

alcohol_DH_class_III

alcohol_DH_class_III: cd08300 (5 - 372)

  • 0
  • 100
  • 200
  • 300
  • 374 a.a.
蛋白主名 其他名称

alcohol dehydrogenase class-3

ADH-B2

FALDH

FDH

GSH-FDH

S-(hydroxymethyl)glutathione dehydrogenase

alcohol dehydrogenase 2

alcohol dehydrogenase B2

alcohol dehydrogenase class-III

class III alcohol dehydrogenase, chi subunit

glutathione-dependent formaldehyde dehydrogenase

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00370 ADH5 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS00371 Adh5 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS00372 Adh5 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Adh5 NCBI NCBI:128
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