2. Gene
  3. ANGPTL7 - angiopoietin like 7 Gene

ANGPTL7 - angiopoietin like 7 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：血管生成素样 7

种属: Homo sapiens

同用名: AngX; CDT6; dJ647M16.1

基因 ID: 10218 | 基因类型: protein coding

关于 ANGPTL7

Cytogenetic location: 1p36.22 Genomic coordinates (GRCh38): 1:11,189,355-11,195,981 (from NCBI)

This gene has 2 transcripts (splice variants), 316 orthologues and 25 paralogues. Broad expression in heart (RPKM 2.5), gall bladder (RPKM 2.2) and 15 other tissues.

功能概要

实现相同的蛋白质结合活性。参与血管系统发育的负调节，参与相机型眼无血管角膜发育和细胞外基质组织的调节。位于胞外区。 [由基因组资源联盟提供，2022 年 4 月]

Enables identical protein binding activity. Involved in negative regulation of vasculature development involved in avascular cornea development in camera-type eye and regulation of extracellular matrix organization. Located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

ANGPTL7 基因产物(1)

mRNA Protein Name
NM_021146.4 NP_066969.1 angiopoietin-related protein 7 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IDA
IDA: 通过直接分析推断
11682471 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25910212 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of vasculature development involved in avascular cornea development in camera-type eye IMP
IMP: 通过突变表型推断
25622036 GOA
involved in regulation of extracellular matrix organization IMP
IMP: 通过突变表型推断
21199193 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular region IDA
IDA: 通过直接分析推断
11682471 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

angiopoietin-related protein 7

angiopoietin-like factor (CDT6)

重组 ANGPTL7 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7509 ANGPTL7/Angiopoietin-related 7 Protein, Human (HEK293, His) O43827 (Q27-P346) ≥95%
HY-P700852 ANGPTL7/Angiopoietin-related 7 Protein, Human (HEK293, hFc) O43827 (Q27-P346) ≥95%
HY-P700955 ANGPTL7/Angiopoietin-related 7 Protein, Human (HEK293, His-Avi) O43827 (Q27-P346) ≥95%

关联疾病

疾病名称 别名
Steroid-Induced Glaucoma

Corticosteroid-Induced Glaucoma
Schnyder Corneal Dystrophy

Schnyder Crystalline Corneal Dystrophy

SCCD

Corneal Dystrophy, Crystalline, Of Schnyder

Corneal Dystrophy, Schnyder Type

Corneal Dystrophy Crystalline Of Schnyder

Crystalline Stromal Dystrophy

Hereditary Crystalline Stromal Dystrophy Of Schnyder

Scd

Corneal Dystrophy, Schnyder

Schnyder Crystalline Dystrophy Sine Crystals

Dystrophy, Corneal, Crystalline, Schnyder
Glaucoma, Primary Open Angle

Glaucoma 1, Open Angle, E

Primary Open Angle Glaucoma

POAG

Adult-Onset Primary Open Angle Glaucoma

Chronic Simple Glaucoma

GLC1E

Primary Open Angle Glaucoma 1e

Glaucoma, Open Angle, Primary
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00696 ANGPTL7 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus ANGPTL7 VGNC VGNC:25895
Canis familiaris ANGPTL7 VGNC VGNC:37863
Macaca mulatta ANGPTL7 VGNC VGNC:69683
Rattus norvegicus ANGPTL7 RGD RGD:7553363
Felis catus ANGPTL7 VGNC VGNC:59783
Mus musculus ANGPTL7 MGD MGI:3605801
Others ANGPTL7 NCBI
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