2. Gene
  3. SYCP2 - synaptonemal complex protein 2 Gene

SYCP2 - synaptonemal complex protein 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：联会复合蛋白 2

种属: Homo sapiens

同用名: SCP2; SCP-2; SPGF1

基因 ID: 10388 | 基因类型: protein coding

关于 SYCP2

Cytogenetic location: 20q13.33 Genomic coordinates (GRCh38): 20:59,863,571-59,933,637 (from NCBI)

This gene has 9 transcripts (splice variants), 84 orthologues, 1 paralogue and is associated with 1 phenotype. Biased expression in testis (RPKM 17.7), stomach (RPKM 1.7) and 4 other tissues.

功能概要

联会复合体是一种蛋白质结构，在减数分裂前期连接同源染色体。由该基因编码的蛋白质是联会复合体的主要成分，可能在支架附着区域结合 DNA。编码的蛋白质需要联会复合蛋白 3，而不是 1，才能包含在联会复合物中。[RefSeq 提供，2008 年 7 月]

The synaptonemal complex is a proteinaceous structure that links homologous chromosomes during the prophase of meiosis. The protein encoded by this gene is a major component of the synaptonemal complex and may bind DNA at scaffold attachment regions. The encoded protein requires synaptonemal complex protein 3, but not 1, for inclusion in the synaptonemal complex. [provided by RefSeq, Jul 2008]

SYCP2 基因产物(1)

mRNA Protein Name
NM_014258.4 NP_055073.2 synaptonemal complex protein 2
蛋白主名 其他名称

synaptonemal complex protein 2

synaptonemal complex lateral element protein

关联疾病

疾病名称 别名
Spermatogenic Failure 1

Oligosynaptic Infertility

SPGF1

Oligochiasmatic Infertility

Oligochiasmic Infertility
Eccrine Papillary Adenocarcinoma

Digital Papillary Adenocarcinoma

Sweat Gland Adenocarcinoma

Digital Papillary Eccrine Carcinoma Of Skin
Eccrine Adenocarcinoma
Tonsil Squamous Cell Carcinoma

Tonsillar Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Palatine Tonsil
Infertility
Spermatogenic Failure

Azoospermia

Spgf

Spermatogenic Failure, Susceptibility To

Absent Sperm

Aspermatogenesis

Infertility Due To Azoospermia

Hypospermatogenesis

Azoospermatism
Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome

Icf Syndrome

Immunodeficiency Syndrome, Variable

Ciid

Centromeric Instability, Immunodeficiency Syndrome

Immune Deficiency, Variable, With Centromeric Instability Of Chromosomes 1, 9, And 16

Icf
Premature Menopause

Primary Ovarian Insufficiency

Premature Ovarian Failure

Hypergonadotropic Hypogonadism

Premature Ovarian Insufficiency

Menopause - Premature

Menopause Praecox

Menopause Premature

Menopause, Premature

Female Hypergonadotropic Hypogonadism

Hypergonadotrophic Ovarian Failure

Primary Female Hypogonadism

Pof - [Premature Ovarian Failure]

Ovarian Failure

Ovarian Secretion Suppression

Ovary Hyposecretion

Ovary Secretion Deficiency

Premature Menopause Nos
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14071 SYCP2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus SYCP2 MGD MGI:1933281
Rattus norvegicus SYCP2 RGD RGD:69429
Macaca mulatta SYCP2 VGNC VGNC:98454
Felis catus SYCP2 VGNC VGNC:65874
Canis familiaris SYCP2 VGNC VGNC:47019
Bos taurus SYCP2 VGNC VGNC:35509
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