2. Gene
  3. PRG3 - proteoglycan 3, pro eosinophil major basic protein 2 Gene

PRG3 - proteoglycan 3, pro eosinophil major basic protein 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：蛋白多糖 3，嗜酸性粒细胞原主要碱性蛋白 2

种属: Homo sapiens

同用名: MBP2; MBPH

基因 ID: 10394 | 基因类型: protein coding

关于 PRG3

Cytogenetic location: 11q12.1 Genomic coordinates (GRCh38): 11:57,376,769-57,381,150 (from NCBI)

This gene has 1 transcript (splice variant), 110 orthologues and 1 paralogue. Restricted expression toward bone marrow (RPKM 15.2).

功能概要

赋予抗压性的细胞外基质结构成分。参与多个过程，包括粒细胞活化；组胺生物合成过程；和基因表达的调控。位于含胶原蛋白的细胞外基质中。 [由基因组资源联盟提供，2022 年 4 月]

An extracellular matrix structural constituent conferring compression resistance. Involved in several processes, including granulocyte activation; histamine biosynthetic process; and regulation of gene expression. Located in collagen-containing extracellular matrix. [provided by Alliance of Genome Resources, Apr 2022]

PRG3 基因产物(1)

mRNA Protein Name
NM_006093.4 NP_006084.2 proteoglycan 3 precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in basophil activation IDA
IDA: 通过直接分析推断
10318872 GOA
involved in histamine biosynthetic process IDA
IDA: 通过直接分析推断
10318872 GOA
involved in leukotriene biosynthetic process IDA
IDA: 通过直接分析推断
10318872 GOA
involved in negative regulation of translation IDA
IDA: 通过直接分析推断
10318872 GOA
involved in neutrophil activation IDA
IDA: 通过直接分析推断
10318872 GOA
involved in positive regulation of interleukin-8 production IDA
IDA: 通过直接分析推断
10318872 GOA
involved in superoxide anion generation IDA
IDA: 通过直接分析推断
10318872 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

PRG3 蛋白结构

Lectin_C

Lectin_C: Lectin C-type domain (118 - 224)

  • 0
  • 100
  • 200
  • 225 a.a.
蛋白主名 其他名称

proteoglycan 3

eosinophil major basic protein homolog

重组 PRG3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71233 PRG3 Protein, Human (HEK293, His) AAI13412.1 (L18-F225) ≥95%

关联疾病

疾病名称 别名
Oropouche Fever

Oropouche Virus Disease

Oropouche Mosquito-Borne Viral Fever
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11089 PRG3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus PRG3 RGD RGD:1309904
Felis catus PRG3 VGNC VGNC:104346
Mus musculus PRG3 MGD MGI:1858200
Macaca mulatta PRG3 VGNC VGNC:76397
Canis familiaris PRG3 VGNC VGNC:52036
Others PRG3 NCBI
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z