2. Gene
  3. Pld4 - phospholipase D family, member 4 Gene

Pld4 - phospholipase D family, member 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: thss

基因 ID: 104759 | 基因类型: protein coding

关于 Pld4

功能概要

Enables single-stranded DNA 5'-3' exodeoxyribonuclease activity. Involved in regulation of cytokine production involved in inflammatory response. Acts upstream of or within hematopoietic progenitor cell differentiation and phagocytosis. Located in several cellular components, including cytoplasmic vesicle; endoplasmic reticulum membrane; and trans-Golgi network membrane. Is expressed in brain and hemolymphoid system. Used to study systemic lupus erythematosus. Orthologous to human PLD4 (Phospholipase D family member 4). [provided by Alliance of Genome Resources, Apr 2022]

Pld4 基因产物(1)

mRNA Protein Name
NM_178911.4 NP_849242.1 5'-3' exonuclease PLD4
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
NOT enables phospholipase D activity IDA
IDA: 通过直接分析推断
21085684 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
18706977 MGI
enables single-stranded DNA 5'-3' DNA exonuclease activity IMP
IMP: 通过突变表型推断
22102906 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within establishment of localization in cell IMP
IMP: 通过突变表型推断
22102906 MGI
acts upstream of or within hematopoietic progenitor cell differentiation IMP
IMP: 通过突变表型推断
24029230 MGI
acts upstream of or within phagocytosis IMP
IMP: 通过突变表型推断
22102906 MGI
involved in regulation of cytokine production involved in inflammatory response IMP
IMP: 通过突变表型推断
22102906 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in early endosome IDA
IDA: 通过直接分析推断
22102906 MGI
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
21085684 MGI
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
21085684 MGI
located in nucleus IDA
IDA: 通过直接分析推断
22102906 MGI
located in phagocytic vesicle IDA
IDA: 通过直接分析推断
22102906 MGI
located in trans-Golgi network membrane IDA
IDA: 通过直接分析推断
21085684 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

5'-3' exonuclease PLD4

PLD 4

choline phosphatase 4

phosphatidylcholine-hydrolyzing phospholipase D4

phospholipase D4

重组 Pld4 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77821 PLD4 Protein, Mouse (HEK293, His) Q8BG07-1 (Q58-W503) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10673 PLD4 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pld4 NCBI NCBI:122618
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