2. Gene
  3. SEMA4F - ssemaphorin 4F Gene

SEMA4F - ssemaphorin 4F Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：信号素 4F

种属: Homo sapiens

同用名: S4F; SEMAM; SEMAW; M-SEMA; PRO2353; m-Sema-M

基因 ID: 10505 | 基因类型: protein coding

关于 SEMA4F

Cytogenetic location: 2p13.1 Genomic coordinates (GRCh38): 2:74,654,247-74,709,713 (from NCBI)

This gene has 10 transcripts (splice variants), 182 orthologues and 19 paralogues. Broad expression in brain (RPKM 2.1), testis (RPKM 1.1) and 22 other tissues.

功能概要

该基因编码跨膜 IV 类信号蛋白家族蛋白，在神经发育中发挥作用。该基因可能参与前列腺癌的神经发生、神经纤维瘤的发展和乳腺癌的肿瘤发生。可变剪接导致多个转录本变体。[RefSeq 提供，2012 年 11 月]

This gene encodes a transmembrane class IV semaphorin family protein, which plays a role in neural development. This gene may be involved in neurogenesis in prostate Cancer, the development of neurofibromas, and breast Cancer tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]

SEMA4F 基因产物(3)

mRNA Protein Name
NM_001271661.2 NP_001258590.1 semaphorin-4F isoform 2 precursor
NM_001271662.2 NP_001258591.1 semaphorin-4F isoform 3 precursor
NM_004263.5 NP_004254.2 semaphorin-4F isoform 1 precursor

SEMA4F 蛋白结构

Sema

Sema: Sema domain (65 - 493)

PSI

PSI: Plexin repeat (512 - 563)

  • 0
  • 200
  • 400
  • 600
  • 770 a.a.
蛋白主名 其他名称

semaphorin-4F

sema domain immunoglobulin domain transmembrane domain (TM) and short cytoplasmic domain (semaphorin) 4F

关联疾病

疾病名称 别名
Dyslexia
Diffuse Glomerulonephritis

Glomerulonephritis Diffuse
Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer
Kallmann Syndrome

Hypogonadism With Anosmia

Kallman'S Syndrome

Anosmic Hypogonadism

Anosmic Idiopathic Hypogonadotropic Hypogonadism

Hypogonadotropic Hypogonadism And Anosmia

Hypogonadotropic Hypogonadism-Anosmia Syndrome

Olfacto-Genital Pathological Sequence

Familial Hypogonadism With Anosmia

Kallman Syndrome

Dysplasia Olfactogenitalis Of De Morsier

Kallmann'S Syndrome

Congenital Hypogonadotropic Hypogonadism With Anosmia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12661 SEMA4F Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta SEMA4F VGNC VGNC:77167
Canis familiaris SEMA4F VGNC VGNC:45997
Bos taurus SEMA4F VGNC VGNC:34437
Mus musculus SEMA4F MGD MGI:1340055
Rattus norvegicus SEMA4F RGD RGD:3658
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