PRDX4 - peroxiredoxin 4 Gene

中文名称：过氧化物酶 4

种属: Homo sapiens

同用名: PRX-4; AOE372; AOE37-2; HEL-S-97n

关于 PRDX4

功能概要

该基因编码的蛋白质是一种抗氧化酶，属于过氧化物酶家族。蛋白质定位于细胞质。过氧化物酶家族的过氧化物酶使用衍生自含硫醇供体分子的还原当量将过氧化氢和烷基氢过氧化物还原成水和醇。已发现这种蛋白质在转录因子 NF-kappaB 的激活中发挥调节作用。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is an antioxidant Enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB. [provided by RefSeq, Jul 2008]