2. Gene
  3. Pi4kb - phosphatidylinositol 4-kinase beta Gene

Pi4kb - phosphatidylinositol 4-kinase beta Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：磷脂酰肌醇 4-激酶 β

种属: Mus musculus

同用名: ESTM41; Pik4cb; PI4Kbeta; PI4K-beta

基因 ID: 107650 | 基因类型: protein coding

关于 Pi4kb

Chromosome 3: 94,882,042-94,914,154 forward strand.GRCm39:CM000996.3

This gene has 7 transcripts (splice variants), 213 orthologues and 9 paralogues. Ubiquitous expression in subcutaneous fat pad adult (RPKM 17.1), bladder adult (RPKM 16.1) and 28 other tissues.

功能概要

预计该基因编码的蛋白具有 1-磷脂酰肌醇 4-激酶活性和 14-3-3 蛋白结合活性。预计参与磷脂酰肌醇磷酸盐生物合成过程和磷脂酰肌醇介导的信号传导。预测位于高尔基体膜；胞质溶胶；和质膜。预计在细胞质和细胞膜中有活性。在椎骨轴肌肉组织中表达。与人 PI4KB（磷脂酰肌醇 4-激酶 β）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable 1-phosphatidylinositol 4-kinase activity and 14-3-3 protein binding activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process and phosphatidylinositol-mediated signaling. Predicted to be located in Golgi membrane; cytosol; and plasma membrane. Predicted to be active in cytoplasm and membrane. Is expressed in vertebral axis musculature. Orthologous to human PI4KB (phosphatidylinositol 4-kinase beta). [provided by Alliance of Genome Resources, Apr 2022]

Pi4kb 基因产物(3)

mRNA Protein Name
NM_001293715.1 NP_001280644.1 phosphatidylinositol 4-kinase beta isoform 1
NM_175356.3 NP_780565.2 phosphatidylinositol 4-kinase beta isoform 2
NM_001293716.1 NP_001280645.1 phosphatidylinositol 4-kinase beta isoform 3

Pi4kb 蛋白结构

PI4KB_NTD

PI4KB_NTD: cd22246 (1 - 65)

PI4Kc_III_beta

PI4Kc_III_beta: cd05168 (513 - 800)

  • 0
  • 200
  • 400
  • 600
  • 801 a.a.
蛋白主名 其他名称

phosphatidylinositol 4-kinase beta

phosphatidylinositol 4-kinase, catalytic, beta polypeptide

ptdIns 4-kinase beta

相关产品

Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-108313 T-00127_HEV1 Inhibitor 99.97% 否
HY-100603 GSK-F1 Inhibitor 95.00% 否
HY-22055B AN-12-H5 intermediate-1 99.72% 否
HY-120900 AN-12-H5 Inhibitor 98.03% 否
HY-W047496 AN-12-H5 intermediate-2 ≥97.0% 否
HY-RS10469 PI4KB Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS10470 Pi4kb Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS10471 Pi4kb Rat Pre-designed siRNA Set A Pre-designed Sets / 否
HY-W451820 AN-12-H5 intermediate-3 95.82% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pi4kb NCBI NCBI:5298
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