CEACAM8 - CEA cell adhesion molecule 8 Gene

中文名称：CEA 细胞粘附分子 8

种属: Homo sapiens

同用名: CD67; CGM6; CD66b; NCA-95

基因 ID: 1088 | 基因类型: protein coding

关于 CEACAM8

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:42,580,243-42,594,924 (from NCBI)

This gene has 2 transcripts (splice variants), 571 orthologues and 24 paralogues. Restricted expression toward bone marrow (RPKM 58.6).

功能概要

启用蛋白质异二聚化活性。通过质膜细胞粘附分子参与异嗜性细胞间粘附。位于细胞表面和细胞外空间。严重急性呼吸系统综合症的生物标志物。 [由基因组资源联盟提供，2022 年 4 月]

Enables protein heterodimerization activity. Involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Located in cell surface and extracellular space. Biomarker of severe acute respiratory syndrome. [provided by Alliance of Genome Resources, Apr 2022]

CEACAM8 基因产物(1)

mRNA	Protein	Name
NM_001816.4	NP_001807.2	carcinoembryonic antigen-related cell adhesion molecule 8 precursor

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	11994468	GOA
enables protein heterodimerization activity	IDA IDA: 通过直接分析推断	26483485	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IMP IMP: 通过突变表型推断	8776764	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in cell surface	IDA IDA: 通过直接分析推断	8776764	GOA
located in extracellular space	IDA IDA: 通过直接分析推断	25645918	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CEACAM8 蛋白结构

V-set

Ig_3

Ig_2

0
100
200
300
349 a.a.

蛋白主名

其他名称

carcinoembryonic antigen-related cell adhesion molecule 8

CD67 antigen

CEACAM8 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	CEACAM8	P31997	CEACAM6	Homo sapiens	P40199	Protein Array	21982860
种属内	CEACAM8	P31997	CEACAM6	Homo sapiens	P40199	ITC	26483485

种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 CEACAM8 蛋白

目录号	产品名	蛋白编号	纯度
HY-P72133	CEACAM8/CD66b Protein, Human (His-SUMO)	P31997 (Q35-D320)	≥95%
HY-P72692	CEACAM8/CD66b Protein, Human (HEK293, His)	P31997 (Q35-H141)	≥95%
HY-P77629	CEACAM8/CD66b Protein, Human (285a.a, HEK293, His)	P31997 (Q35-S319)	≥95%

CEACAM8 抗体

目录号	产品名	应用	反应物种
HY-P82326	CD66b Antibody (YA2071)	WB	Human

关联疾病

疾病名称

别名

Paroxysmal Nocturnal Hemoglobinuria

Marchiafava-Micheli Disease	Pnh
Hemoglobinuria, Paroxysmal	Marchiafava-Micheli Syndrome
Paroxysmal Hemoglobinuria Nocturnal	Nocturnal Haemoglobinuria
Nocturnal Paroxysmal Haematuria	Nocturnal Paroxysmal Haemoglobinaemia

Hemoglobinuria

Reactive Arthritis

Postdysenteric Arthropathy	Reiter Disease
Pira	Reiter Syndrome
Reiters Syndrome	Arthritis, Reactive
Fiessinger Leroy Reiter Syndrome	Post-Bacterial Arthropathy
Reiter'S Disease	Post-Infectious Arthritis
Post-Infectious Reactive Arthropathy	Reiter'S Syndrome
Arthritis Urethritica	Fiessinger-Leroy Disease
Polyarthritis Enterica	Venereal Arthritis
Arthritis Reactive	Post-Dysenteric Arthropathy
Arthritis, Venereal

Endocarditis

Developmental And Epileptic Encephalopathy 38

DEE38	Epileptic Encephalopathy, Early Infantile, 38
Eiee38	Developmental And Epileptic Encephalopathy, 38
Glycosylphosphatidylinositol Biosynthesis Defect 23	Gpibd23
Early Infantile Epileptic Encephalopathy 38

Myelofibrosis

Primary Myelofibrosis	Agnogenic Myeloid Metaplasia
Idiopathic Myelofibrosis	Myeloid Metaplasia
Myelofibrosis With Myeloid Metaplasia	Osteomyelofibrosis
Megakaryocytic Myelosclerosis	Myelosclerosis
Chronic Idiopathic Myelofibrosis	Myelofibrosis, Idiopathic
Myelofibrosis With Myeloid Metaplasia, Somatic	Myelofibrosis, Somatic
Aleukemic Myelosis	Bone Marrow Fibrosis
MYELOF	MMM
Agnogenic Myeloid Metaplasia With Myelofibrosis	Ammm
Myelosclerosis With Myeloid Metaplasia	Myelofibrosis Nos

Leukemia, Chronic Myeloid

Chronic Myeloid Leukemia	Chronic Myelogenous Leukemia
CML	Chronic Granulocytic Leukemia
Leukemia, Philadelphia Chromosome-Positive, Resistant To Imatinib	Chronic Myeloid Leukaemia
Chronic Granulocytic Leukaemia	Chronic Myelogenous Leukaemia
Myeloid Leukemia, Chronic	Leukemia, Chronic Myelogenous
Leukemia, Chronic Myeloid, Philadelphia Chromosome Positive, Somatic	Cml - Chronic Myelogenous Leukemia
Cgl	Chronic Myelocytic Leukemia
Leukemia, Chronic Myeloid, Atypical	ACML
Atypical Chronic Myeloid Leukemia Bcr-Abl1 Negative	Myeloid Leukemia Chronic
Leukemia, Myeloid, Chronic	Leukemia, Myeloid, Chronic, Atypical, Bcr-Abl Negative
Cml- [Chronic Myeloid Leukaemia]	Cgl - [Chronic Granulocytic Leukaemia]
Chronic Myelocytic Leukaemia

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS02444	CEACAM8 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	CEACAM8	MGD	MGI:1891352
Canis familiaris	CEACAM8	NCBI
Others	CEACAM8	NCBI

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

CEACAM8 - CEA cell adhesion molecule 8 Gene

关于 CEACAM8

功能概要

CEACAM8 基因产物(1)

CEACAM8 蛋白结构

CEACAM8 蛋白互作信息

重组 CEACAM8 蛋白

CEACAM8 抗体

关联疾病

直系同源

热门区域

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CEACAM8 - CEA cell adhesion molecule 8 Gene

关于 CEACAM8

功能概要

CEACAM8 基因产物(1)

CEACAM8 蛋白结构

CEACAM8 蛋白互作信息

重组 CEACAM8 蛋白

CEACAM8 抗体

关联疾病

相关产品

直系同源

热门区域

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B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z