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  2. GPR182 - G protein-coupled receptor 182 Gene

GPR182 - G protein-coupled receptor 182 Gene

中文名称:G 蛋白偶联受体 182

种属: Homo sapiens

同用名: AMR; 7TMR; ADMR; AM-R; G10D; L1-R; gamrh; hrhAMR

基因 ID: 11318 | 基因类型: protein coding

关于 GPR182

Cytogenetic location: 12q13.3 Genomic coordinates (GRCh38): 12:56,994,492-56,998,877 (from NCBI)

This gene has 3 transcripts (splice variants), 191 orthologues and 1 paralogue. Biased expression in spleen (RPKM 5.1), testis (RPKM 0.9) and 4 other tissues.

功能概要

肾上腺髓质素是一种有效的血管舒张肽,对心血管功能有重要影响。该基因编码属于 G 蛋白偶联受体家族 1 的七次跨膜蛋白。对大鼠对应物的研究表明,编码的蛋白质可能作为肾上腺髓质素的受体发挥作用。[RefSeq 提供,2008 年 7 月]

Adrenomedullin is a potent vasodilator peptide that exerts major effects on cardiovascular function. This gene encodes a seven-transmembrane protein that belongs to the family 1 of G-protein coupled receptors. Studies of the rat counterpart suggest that the encoded protein may function as a receptor for Adrenomedullin. [provided by RefSeq, Jul 2008]

GPR182 基因产物(1)

mRNA Protein Name
NM_007264.4 NP_009195.1 G-protein coupled receptor 182

GPR182 蛋白结构

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (70 - 320)

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  • 404 a.a.
蛋白主名 其他名称

G-protein coupled receptor 182

adrenomedullin receptor

GPR182 抗体

目录号 产品名 应用 反应物种
HY-P83216 GPR182 Antibody (YA2961) WB Human, Mouse, Rat

关联疾病

疾病名称 别名
Lipoma Of Spermatic Cord

Spermatic Cord Lipoma

Paratesticular Lipoma
Renal Hypertension

Hypertension Renal

Hypertension, Renal

Oligohydramnios

Oligohydramnios - Delivered

Antepartum Oligohydramnios

Delivered Oligohydramnios

Oligohydramnios, Antepartum Condition Or Complication

Deficient Liquor

Oligohydramnios, Unspecified Trimester

Reduced Liquor Volume

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus GPR182 RGD RGD:61903
Mus musculus GPR182 MGD MGI:109545
Canis familiaris GPR182 VGNC VGNC:41422
Bos taurus GPR182 VGNC VGNC:29576
Macaca mulatta GPR182 VGNC VGNC:72936