1. Gene
  2. Cpb2 - carboxypeptidase B2 Gene

Cpb2 - carboxypeptidase B2 Gene

种属: Rattus norvegicus

基因 ID: 113936 | 基因类型: protein coding

关于 Cpb2

功能概要

Enables Carboxypeptidase activity. Involved in several processes, including liver regeneration; negative regulation of hepatocyte proliferation; and regulation of blood coagulation. Located in extracellular space. Human ortholog(s) of this gene implicated in chronic kidney disease. Orthologous to human CPB2 (Carboxypeptidase B2). [provided by Alliance of Genome Resources, Apr 2022]

Cpb2 基因产物(1)

mRNA Protein Name
NM_053617.2 NP_446069.1 carboxypeptidase B2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables carboxypeptidase activity IDA
IDA: 通过直接分析推断
11021404 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to glucose stimulus IEP
IEP: 通过表达模式推断
23369837 RGD
involved in fibrinolysis IMP
IMP: 通过突变表型推断
11848438 RGD
involved in liver regeneration IEP
IEP: 通过表达模式推断
19386599 RGD
involved in negative regulation of fibrinolysis IDA
IDA: 通过直接分析推断
17002650 RGD
involved in negative regulation of hepatocyte proliferation IMP
IMP: 通过突变表型推断
19386599 RGD
involved in negative regulation of plasminogen activation IMP
IMP: 通过突变表型推断
23369837 RGD
involved in positive regulation of extracellular matrix constituent secretion IMP
IMP: 通过突变表型推断
23369837 RGD
involved in protein catabolic process IDA
IDA: 通过直接分析推断
11021404 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
17911187 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
17911187 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

carboxypeptidase B2

CPR

CPU

TAFI

carboxypeptidase B2 (plasma)

carboxypeptidase R

carboxypeptidase U

thrombin-activable fibrinolysis inhibitor

重组 Cpb2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75449 Carboxypeptidase B2/CPB2 Protein, Rat (HEK293, His) Q9EQV9 (F22-S422) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cpb2 NCBI NCBI:1361
Mus musculus Cpb2 NCBI NCBI:56373