2. Gene
  3. Adipoq - adiponectin, C1Q and collagen domain containing Gene

Adipoq - adiponectin, C1Q and collagen domain containing Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ad; APN; Acdc; Adid; apM1; 30kDa; GBP28; adipo; Acrp30

基因 ID: 11450 | 基因类型: protein coding

关于 Adipoq

功能概要

Enables hormone activity and identical protein binding activity. Involved in several processes, including detection of oxidative stress; negative regulation of cold-induced thermogenesis; and regulation of protein serine/threonine kinase activity. Acts upstream of or within with a positive effect on gene expression. Acts upstream of or within several processes, including brown fat cell differentiation; negative regulation of gluconeogenesis; and positive regulation of glucose import. Located in endoplasmic reticulum and extracellular space. Is expressed in several structures, including adipose tissue; axial musculature; gut; male reproductive gland or organ; and serum. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); cardiovascular system disease (multiple); non-alcoholic fatty liver disease; primary open angle glaucoma; and type 2 diabetes mellitus. Orthologous to human ADIPOQ (Adiponectin, C1q and collagen domain containing). [provided by Alliance of Genome Resources, Apr 2022]

Adipoq 基因产物(1)

mRNA Protein Name
NM_009605.5 NP_033735.3 adiponectin precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables hormone activity IDA
IDA: 通过直接分析推断
11479628 MGI
enables identical protein binding IPI
IPI: 通过物理相互作用推断
7592907 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12802337 MGI
enables protein serine/threonine kinase activator activity IDA
IDA: 通过直接分析推断
20667975 MGI
enables signaling receptor binding IDA
IDA: 通过直接分析推断
12087086 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within brown fat cell differentiation IDA
IDA: 通过直接分析推断
18492766 MGI
acts upstream of or within cellular response to insulin stimulus IGI
IGI: 通过遗传相互作用推断
17693256 MGI
involved in cellular response to xenobiotic stimulus IDA
IDA: 通过直接分析推断
19109165 MGI
involved in detection of oxidative stress IMP
IMP: 通过突变表型推断
18431508 MGI
acts upstream of or within fatty acid beta-oxidation IMP
IMP: 通过突变表型推断
12151381 MGI
acts upstream of or within fatty acid oxidation IDA
IDA: 通过直接分析推断
12802337 MGI
acts upstream of or within positive effect gene expression IDA
IDA: 通过直接分析推断
23015294 MGI
acts upstream of or within glucose homeostasis IDA
IDA: 通过直接分析推断
11479628 MGI
acts upstream of or within glucose homeostasis IMP
IMP: 通过突变表型推断
12032136 MGI
acts upstream of or within glucose metabolic process IDA
IDA: 通过直接分析推断
11479628 MGI
acts upstream of or within glucose metabolic process IMP
IMP: 通过突变表型推断
12032136 MGI
involved in negative regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
18431508 MGI
involved in negative regulation of MAP kinase activity IDA
IDA: 通过直接分析推断
19460854 MGI
involved in negative regulation of cell migration IDA
IDA: 通过直接分析推断
19460854 MGI
involved in negative regulation of cold-induced thermogenesis IMP
IMP: 通过突变表型推断
24531262 MGI
involved in negative regulation of fat cell differentiation IDA
IDA: 通过直接分析推断
12021245 MGI
acts upstream of or within negative regulation of gluconeogenesis IDA
IDA: 通过直接分析推断
11479628 MGI
involved in negative regulation of inflammatory response IDA
IDA: 通过直接分析推断
19109165 MGI
involved in negative regulation of metanephric mesenchymal cell migration IDA
IDA: 通过直接分析推断
19460854 MGI
involved in negative regulation of platelet-derived growth factor receptor signaling pathway IDA
IDA: 通过直接分析推断
19460854 MGI
involved in negative regulation of platelet-derived growth factor receptor-alpha signaling pathway IDA
IDA: 通过直接分析推断
19460854 MGI
acts upstream of or within positive regulation of D-glucose import IDA
IDA: 通过直接分析推断
12068289 MGI
involved in positive regulation of cAMP-dependent protein kinase activity IMP
IMP: 通过突变表型推断
18431508 MGI
acts upstream of or within positive regulation of canonical NF-kappaB signal transduction IDA
IDA: 通过直接分析推断
12087086 MGI
involved in positive regulation of cold-induced thermogenesis IMP
IMP: 通过突变表型推断
24531262 MGI
acts upstream of or within positive regulation of fatty acid metabolic process IMP
IMP: 通过突变表型推断
12068289 MGI
involved in positive regulation of metanephric podocyte development IMP
IMP: 通过突变表型推断
18431508 MGI
involved in positive regulation of renal albumin absorption IMP
IMP: 通过突变表型推断
18431508 MGI
acts upstream of or within positive regulation of signal transduction IDA
IDA: 通过直接分析推断
12087086 MGI
acts upstream of or within response to bacterium IEP
IEP: 通过表达模式推断
23012479 MGI
acts upstream of or within response to glucose IDA
IDA: 通过直接分析推断
12068289 MGI
acts upstream of or within response to glucose IMP
IMP: 通过突变表型推断
12032136 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
10444069 MGI
located in extracellular space IDA
IDA: 通过直接分析推断
7592907 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

adiponectin

30 kDa adipocyte complement-related protein

adipocyte complement related protein

adipocyte complement-related 30 kDa protein

adipocyte, C1Q and collagen domain containing

adipocyte, C1q and collagen domain-containing protein

adipocyte-specific protei

重组 Adipoq 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7129 Adiponectin/Acrp30 Protein, Mouse (227a.a) Q60994 (V21-N247) ≥95%
HY-P7358 Adiponectin/Acrp30 Protein, Mouse (144a.a) Q60994 (K104-N247,V113M) ≥95%
HY-P7461 Adiponectin/Acrp30 Protein, Mouse (HEK293, His) Q60994 (E18-N247) ≥95%
HY-P78234 Adiponectin/Acrp30 Protein, Mouse (HEK293, Fc) Q60994 (E18-N247) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00378 ADIPOQ Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Adipoq NCBI NCBI:9370
Macaca fascicularis Adipoq NCBI NCBI:102123471
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