SLC26A9 - solute carrier family 26 member 9 Gene

中文名称：溶质载体家族 26 成员 9

种属: Homo sapiens

基因 ID: 115019 | 基因类型: protein coding

关于 SLC26A9

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:205,913,052-205,943,456 (from NCBI)

This gene has 6 transcripts (splice variants), 187 orthologues, 9 paralogues and is associated with 1 phenotype. Biased expression in salivary gland (RPKM 19.0), stomach (RPKM 12.3) and 5 other tissues.

功能概要

该基因是硫酸盐/阴离子转运基因家族的成员之一。家族成员的基因组 (外显子的数量和大小) 和蛋白质 (物种间的长度) 结构非常保守，但组织表达模式却明显不同。该基因的产物是由 WNK 激酶调节的高选择性氯离子通道。可变剪接导致编码不同异构体的多个转录变体。[RefSeq 提供，2008 年 12 月]

This gene is one member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures yet have markedly different tissue expression patterns. The product of this gene is a highly selective chloride ion channel regulated by WNK kinases. Alternative splicing results in multiple transcript variants encoding differing isoforms.[provided by RefSeq, Dec 2008]

SLC26A9 基因产物(2)

mRNA	Protein	Name
NM_052934.4	NP_443166.1	solute carrier family 26 member 9 isoform a
NM_134325.3	NP_599152.2	solute carrier family 26 member 9 isoform b

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables ATPase binding	IPI IPI: 通过物理相互作用推断	19289574	GOA
enables chloride channel activity	IDA IDA: 通过直接分析推断	17673510	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	28360110	GOA
enables solute:inorganic anion antiporter activity	IDA IDA: 通过直接分析推断	15800055	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in chloride transmembrane transport	IDA IDA: 通过直接分析推断	15800055	GOA
involved in chloride transport	IDA IDA: 通过直接分析推断	17673510	GOA
involved in monoatomic anion transport	IDA IDA: 通过直接分析推断	17673510	GOA
involved in positive regulation of gene expression	IDA IDA: 通过直接分析推断	20658517	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
is active in Golgi membrane	IDA IDA: 通过直接分析推断	26801567	GOA
located in apical plasma membrane	IDA IDA: 通过直接分析推断	20658517	GOA
located in cell surface	IDA IDA: 通过直接分析推断	17673510	GOA
is active in endoplasmic reticulum membrane	IDA IDA: 通过直接分析推断	26801567	GOA
is active in endosome membrane	IDA IDA: 通过直接分析推断	26801567	GOA
is active in plasma membrane	IDA IDA: 通过直接分析推断	26801567	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SLC26A9 蛋白结构

Sulfate_transp

STAS

0
200
400
600
791 a.a.

蛋白主名

其他名称

solute carrier family 26 member 9

anion transporter/exchanger protein 9

关联疾病

疾病名称

别名

Cystic Fibrosis

Mucoviscidosis	CF
Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis	Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis
Cystic Fibrosis Lung Disease, Modifier Of	Cystic Fibrosis Of Pancreas
Fibrocystic Disease Of Pancreas	Cf - [Cystic Fibrosis]
Cystic Fibrosis Nos	Fibrocystic Disease
Fibrocystic Disease Of The Pancreas	Mucoviscidosis Of Pancreas
Nonproliferative Fibrocystic Disease	Pancreatic Cystic Fibrosis

Ileus

Ileus Of Intestine

Parotid Gland Cancer

Cancer Of Parotid Gland	Parotid Neoplasms
Malignant Neoplasm Of The Parotid	Malignant Tumor Of Parotid Gland
Parotid Cancer	Parotid Neoplasm
Parotid Gland Carcinoma	Cancer Of Parotid
Malignant Tumour Of Parotid Gland	Parotid Duct Cancer
Parotid Ductal Cancer	Parotid Glandular Cancer
Primary Malignant Neoplasm Of Parotid Gland

Pendred Syndrome

Goiter-Deafness Syndrome	Deafness With Goiter
PDS	Thyroid Dyshormonogenesis 2b
Tdh2b	Autosomal Recessive Sensorineural Hearing Impairment And Goiter
Pendred'S Syndrome	Thyroid Hormonogenesis, Genetic Defect In, 2b
Hypothyroidism, Congenital, Due To Dyshormonogenesis, 2b	Congenital Hypothyroidism Due To Dyshormonogenesis 2b
Genetic Defect In Thyroid Hormonogenesis 2b	Autosomal Recessive Sensorineural Hearing Impairment, Enlarged Vestibular Aqueduct, And Goiter
Goiter-Hearing Loss Syndrome	Goitre-Deafness Syndrome
Goitre Deafness

Intestinal Obstruction

Inspissated Milk Syndrome

Milk Curd Syndrome

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-159706	S9-A13	Inhibitor	99.68%	否
HY-RS13143	SLC26A9 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	SLC26A9	MGD	MGI:2444594
Bos taurus	SLC26A9	VGNC	VGNC:34784
Macaca mulatta	SLC26A9	VGNC	VGNC:77480
Felis catus	SLC26A9	VGNC	VGNC:65287
Canis familiaris	SLC26A9	VGNC	VGNC:46328
Rattus norvegicus	SLC26A9	RGD	RGD:1310441
Others	SLC26A9	NCBI

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。	站点地图隐私声明
沪ICP备15051369号-4 上海工商沪公网安备31011502019417 沪(浦)应急管危经许[2021]201709(QFYS) 营业执照（三证合一）
Copyright © 2013-2025 MedChemExpress. All Rights Reserved.

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

SLC26A9 - solute carrier family 26 member 9 Gene

关于 SLC26A9

功能概要

SLC26A9 基因产物(2)

SLC26A9 蛋白结构

关联疾病

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

姓名
邮箱 *

Sorry, but the email address you supplied was invalid.

SLC26A9 - solute carrier family 26 member 9 Gene

关于 SLC26A9

功能概要

SLC26A9 基因产物(2)

SLC26A9 蛋白结构

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z