SLC26A7 - solute carrier family 26 member 7 Gene

中文名称：溶质载体家族 26 成员 7

种属: Homo sapiens

同用名: SUT2

基因 ID: 115111 | 基因类型: protein coding

关于 SLC26A7

Cytogenetic location: 8q21.3 Genomic coordinates (GRCh38): 8:91,209,496-91,398,155 (from NCBI)

This gene has 10 transcripts (splice variants), 139 orthologues and 9 paralogues. Restricted expression toward thyroid (RPKM 194.6).

功能概要

该基因是硫酸盐/阴离子转运基因家族的成员之一。家族成员在基因结构和蛋白质长度方面非常保守，但具有明显不同的组织表达模式。该基因在肾脏中具有丰富且特异的表达。已经描述了编码不同亚型的可变剪接转录物变体。[RefSeq 提供，2013 年 8 月]

This gene is one member of a family of sulfate/anion transporter genes. Family members are well conserved in gene structure and protein length yet have markedly different tissue expression patterns. This gene has abundant and specific expression in the kidney. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Aug 2013]

SLC26A7 基因产物(4)

mRNA	Protein	Name
NM_001282356.2	NP_001269285.1	anion exchange transporter isoform a
NM_001282357.2	NP_001269286.1	anion exchange transporter isoform c
NM_052832.4	NP_439897.1	anion exchange transporter isoform a
NM_134266.2	NP_599028.1	anion exchange transporter isoform b

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables chloride channel activity	IDA IDA: 通过直接分析推断	11834742	GOA
enables chloride:bicarbonate antiporter activity	IDA IDA: 通过直接分析推断	12736153	GOA
enables oxalate transmembrane transporter activity	IDA IDA: 通过直接分析推断	11834742	GOA
enables sulfate transmembrane transporter activity	IDA IDA: 通过直接分析推断	11834742	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in chloride transport	IDA IDA: 通过直接分析推断	11834742	GOA
involved in iodide transport	IMP IMP: 通过突变表型推断	31372509	GOA
involved in oxalate transport	IDA IDA: 通过直接分析推断	11834742	GOA
involved in sulfate transmembrane transport	IDA IDA: 通过直接分析推断	11834742	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in apical plasma membrane	IDA IDA: 通过直接分析推断	31372509	GOA
located in basolateral plasma membrane	IDA IDA: 通过直接分析推断	30333321	GOA
located in basolateral plasma membrane	IMP IMP: 通过突变表型推断	16524946	GOA
located in cytoplasm	IDA IDA: 通过直接分析推断	16524946	GOA
located in endosome	IDA IDA: 通过直接分析推断	16524946	GOA
located in lateral plasma membrane	IDA IDA: 通过直接分析推断	31372509	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SLC26A7 蛋白结构

Sulfate_transp

STAS

0
200
400
600
656 a.a.

蛋白主名

其他名称

anion exchange transporter

solute carrier family 26 (anion exchanger), member 7

关联疾病

疾病名称

别名

Congenital Hypothyroidism

Cretinism	Neonatal Hypothyroidism
Ch	Cht
Congenital Myxedema	Myxedema, Congenital
Endemic Cretinism	Congenital Iodine-Deficiency Syndrome
Fetal Iodine Deficiency Syndrome	Congenital Iodine-Deficiency Hypothyroidism Nos

Dyshormonogenic Goiter

Dyshormonogenic Goitre

Pendred Syndrome

Goiter-Deafness Syndrome	Deafness With Goiter
PDS	Thyroid Dyshormonogenesis 2b
Tdh2b	Autosomal Recessive Sensorineural Hearing Impairment And Goiter
Pendred'S Syndrome	Thyroid Hormonogenesis, Genetic Defect In, 2b
Hypothyroidism, Congenital, Due To Dyshormonogenesis, 2b	Congenital Hypothyroidism Due To Dyshormonogenesis 2b
Genetic Defect In Thyroid Hormonogenesis 2b	Autosomal Recessive Sensorineural Hearing Impairment, Enlarged Vestibular Aqueduct, And Goiter
Goiter-Hearing Loss Syndrome	Goitre-Deafness Syndrome
Goitre Deafness

Diastrophic Dysplasia

Diastrophic Dwarfism	DTD
Dd	Diastrophic Dysplasia, Broad Bone-Platyspondylic Variant
Dysplasia, Diastrophic	Diastrophic Dysplasia Variant

Renal Tubular Acidosis

Acidosis Renal Tubular	Acidosis, Renal Tubular
Lightwood-Albright Syndrome	Lightwood Syndrome
Idiopathic Infantile Hypercalcemia - Mild Form	Kidney Tubular Acidosis
Renal Tubule Acidosis	Kidney Acidosis
Renal Acidosis	Renal Hyperchloremic Acidosis
Rta - [Renal Tubular Acidosis]

Hypothyroidism

Thyroid Diseases	Thyroid Disease
Thyroid Deficiency	Thyroid Insufficiency
Dysfunction Thyroid	Thyroid Dysfunction

Brown-Vialetto-Van Laere Syndrome 2

BVVLS2	Rfvt3-Related Riboflavin Transporter Deficiency
Rtd3	Riboflavin Transporter Deficiency 3
Brown-Vialetto-Van Laere Syndrome, Type 2

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS13141	SLC26A7 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	SLC26A7	MGD	MGI:2384791
Canis familiaris	SLC26A7	VGNC	VGNC:46326
Rattus norvegicus	SLC26A7	RGD	RGD:1310846
Bos taurus	SLC26A7	VGNC	VGNC:34782
Felis catus	SLC26A7	VGNC	VGNC:65285
Macaca mulatta	SLC26A7	VGNC	VGNC:77478

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。	站点地图隐私声明
沪ICP备15051369号-4 上海工商沪公网安备31011502019417 沪(浦)应急管危经许[2021]201709(QFYS) 营业执照（三证合一）
Copyright © 2013-2025 MedChemExpress. All Rights Reserved.

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

SLC26A7 - solute carrier family 26 member 7 Gene

关于 SLC26A7

功能概要

SLC26A7 基因产物(4)

SLC26A7 蛋白结构

关联疾病

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

姓名
邮箱 *

Sorry, but the email address you supplied was invalid.

SLC26A7 - solute carrier family 26 member 7 Gene

关于 SLC26A7

功能概要

SLC26A7 基因产物(4)

SLC26A7 蛋白结构

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z