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  2. Aldh3a1 - aldehyde dehydrogenase family 3, subfamily A1 Gene

Aldh3a1 - aldehyde dehydrogenase family 3, subfamily A1 Gene

中文名称:醛脱氢酶 家族 3 ,亚家族 A1

种属: Mus musculus

同用名: Ahd4; Aldh; Ahd-4; Aldh3

基因 ID: 11670 | 基因类型: protein coding

关于 Aldh3a1

Chromosome 11: 61,098,363-61,109,247 forward strand.GRCm39:CM001004.3

This gene has 3 transcripts (splice variants), 370 orthologues, 19 paralogues and is associated with 1 phenotype. Biased expression in bladder adult (RPKM 55.3), stomach adult (RPKM 53.6) and 1 other tissue.

功能概要

该基因编码的蛋白可启动 3-氯烯丙基醛脱氢酶活性和醛脱氢酶 (NAD+) 活性。预计将参与多个过程,包括对 cAMP 的响应;对糖皮质激素的反应;和对缺氧的反应。位于细胞质中。是膜的组成部分。以多种结构表达,包括消化系统;蜕膜;早孕;性腺;和肝脏。该基因的人类直系同源物与动脉硬化有关。与人类 ALDH3A1(醛脱氢酶 3 家族成员 A1)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables 3-chloroallyl aldehyde dehydrogenase activity and aldehyde dehydrogenase (NAD+) activity. Predicted to be involved in several processes, including response to cAMP; response to glucocorticoid; and response to hypoxia. Located in cytoplasm. Is integral component of membrane. Is expressed in several structures, including alimentary system; decidua; early conceptus; gonad; and liver. Human ortholog(s) of this gene implicated in arteriosclerosis. Orthologous to human ALDH3A1 (aldehyde dehydrogenase 3 family member A1). [provided by Alliance of Genome Resources, Apr 2022]

Aldh3a1 基因产物(3)

mRNA Protein Name
NM_007436.2 NP_031462.2 aldehyde dehydrogenase, dimeric NADP-preferring isoform 1
NM_001112725.1 NP_001106196.1 aldehyde dehydrogenase, dimeric NADP-preferring isoform 1
NM_001331112.1 NP_001318041.1 aldehyde dehydrogenase, dimeric NADP-preferring isoform 2
基因本体论
  • 分子功能
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
25286108 MGI
located in membrane IDA
IDA: 通过直接分析推断
25286108 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Aldh3a1 蛋白结构

ALDH_F3AB

ALDH_F3AB: cd07132 (4 - 446)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 453 a.a.
蛋白主名 其他名称

aldehyde dehydrogenase, dimeric NADP-preferring

alcohol dehydrogenase family 3, subfamily A1

aldehyde dehydrogenase 3, stomach cytosolic (class 3)

aldehyde dehydrogenase 4

aldehyde dehydrogenase family 3 member A1

dioxin-inducible aldehyde dehydrogenase 3

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Aldh3a1 NCBI NCBI:218