1. Gene
  2. Rps6ka2 - ribosomal protein S6 kinase A2 Gene

Rps6ka2 - ribosomal protein S6 kinase A2 Gene

中文名称:核糖体蛋白 S6 激酶 A2

种属: Rattus norvegicus

基因 ID: 117269 | 基因类型: protein coding

关于 Rps6ka2

Primary_assembly 1: 52,631,736-52,906,739 forward strand.mRatBN7.2:CM026974.1

This gene has 6 transcripts (splice variants), 209 orthologues, 7 paralogues and is associated with 2 phenotypes. Biased expression in Muscle (RPKM 261.6), Heart (RPKM 95.4) and 7 other tissues.

功能概要

预测该基因编码的蛋白编码的蛋白可启动蛋白丝氨酸/苏氨酸/酪氨酸激酶活性和核糖体蛋白 S6 激酶活性。预计参与多个过程,包括细胞群增殖的负调控;肽基丝氨酸磷酸化;和细胞凋亡过程的正调控。预计在几个过程的上游或内部起作用,包括心肌细胞凋亡过程;卵母细胞成熟;和基因表达的调控。预测位于减数分裂纺锤体和细胞核。预计在细胞质和核质中有活性。与人 RPS6KA2(核糖体蛋白 S6 激酶 A2)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable protein serine/threonine/tyrosine kinase activity and ribosomal protein S6 kinase activity. Predicted to be involved in several processes, including negative regulation of cell population proliferation; peptidyl-serine phosphorylation; and positive regulation of apoptotic process. Predicted to act upstream of or within several processes, including cardiac muscle cell apoptotic process; oocyte maturation; and regulation of gene expression. Predicted to be located in meiotic spindle and nucleus. Predicted to be active in cytoplasm and nucleoplasm. Orthologous to human RPS6KA2 (ribosomal protein S6 kinase A2). [provided by Alliance of Genome Resources, Apr 2022]

Rps6ka2 基因产物(1)

mRNA Protein Name
NM_057128.1 NP_476469.1 ribosomal protein S6 kinase alpha-2

Rps6ka2 蛋白结构

STKc_RSK_N

STKc_RSK_N: cd05582 (91 - 407)

STKc_RSK3_C

STKc_RSK3_C: cd14178 (439 - 731)

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  • 762 a.a.
蛋白主名 其他名称

ribosomal protein S6 kinase alpha-2

ribosomal protein S6 kinase polypeptide 2

ribosomal protein S6 kinase, 90kD, polypeptide 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rps6ka2 NCBI NCBI:6196