2. Gene
  3. Calca - calcitonin/calcitonin-related polypeptide, alpha Gene

Calca - calcitonin/calcitonin-related polypeptide, alpha Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CA; Ct; Ctn; Calc; Cgrp; CGRP1; Calc1; CGRP-1

基因 ID: 12310 | 基因类型: protein coding

关于 Calca

功能概要

This gene encodes the peptide hormones Calcitonin, Calcitonin gene-related peptide (CGRP) and katacalcin. Alternative splicing of the mRNA results in multiple variants that encode either Calcitonin or CGRP preproproteins. Post-translational processing of the Calcitonin and CGRP propeptides results in either Calcitonin and katacalcin, or CGRP, respectively. Calcitonin and katacalcin modulate calcium levels in the blood stream. CGRP can function as a vasodilator and play a role in the transmission of pain. The human homolog of CGRP was found to have antimicrobial activity. [provided by RefSeq, Mar 2015]

Calca 基因产物(4)

mRNA Protein Name
NM_001033954.3 NP_001029126.1 calcitonin gene-related peptide 1 isoform Cgrp preproprotein
NM_001289444.1 NP_001276373.1 calcitonin gene-related peptide 1 isoform Cgrp preproprotein
NM_001305616.1 NP_001292545.1 calcitonin gene-related peptide 1 isoform Calca preproprotein
NM_007587.2 NP_031613.2 calcitonin gene-related peptide 1 isoform Calca preproprotein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcitonin receptor binding IDA
IDA: 通过直接分析推断
9322931 MGI
enables signaling receptor binding IDA
IDA: 通过直接分析推断
7698182 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within activation of adenylate cyclase activity IDA
IDA: 通过直接分析推断
8582325 MGI
acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
8582325 MGI
acts upstream of or within artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure IMP
IMP: 通过突变表型推断
11717154 MGI
acts upstream of or within cellular response to nerve growth factor stimulus IDA
IDA: 通过直接分析推断
24760869 MGI
acts upstream of or within detection of temperature stimulus involved in sensory perception of pain IMP
IMP: 通过突变表型推断
16118273 MGI
acts upstream of or within feeding behavior IDA
IDA: 通过直接分析推断
8735980 MGI
acts upstream of or within inflammatory response IDA
IDA: 通过直接分析推断
7698182 MGI
acts upstream of or within intracellular calcium ion homeostasis IGI
IGI: 通过遗传相互作用推断
12488435 MGI
acts upstream of or within negative regulation of blood pressure IMP
IMP: 通过突变表型推断
10642343 MGI
acts upstream of or within negative regulation of ossification IMP
IMP: 通过突变表型推断
12488435 MGI
acts upstream of or within negative regulation of smooth muscle contraction IDA
IDA: 通过直接分析推断
9322931 MGI
acts upstream of or within neuropeptide signaling pathway IDA
IDA: 通过直接分析推断
7698182 MGI
acts upstream of ossification IMP
IMP: 通过突变表型推断
12488435 MGI
acts upstream of or within response to heat IMP
IMP: 通过突变表型推断
11166483 MGI
acts upstream of or within response to pain IMP
IMP: 通过突变表型推断
10208559 MGI
acts upstream of smooth muscle contraction IDA
IDA: 通过直接分析推断
9322931 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
7521790 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
9271704 MGI
located in extracellular region IDA
IDA: 通过直接分析推断
8735980 MGI
located in intracellular anatomical structure IDA
IDA: 通过直接分析推断
7955356 MGI
located in neuron projection IDA
IDA: 通过直接分析推断
11466438 MGI
located in terminal bouton IDA
IDA: 通过直接分析推断
8453761 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

calcitonin gene-related peptide 1

alpha-type CGRP

calcitonin gene-related peptide I

重组 Calca 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77587 Calcitonin/CALCA Protein, Mouse (HEK293, Fc) Q99JA0 (V26-F119) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01828 CALCA Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Calca NCBI NCBI:796
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