1. Gene
  2. Capn1 - calpain 1 Gene

Capn1 - calpain 1 Gene

种属: Mus musculus

同用名: Capa1; Capa-1; mu-calpin

基因 ID: 12333 | 基因类型: protein coding

关于 Capn1

功能概要

Enables calcium-dependent cysteine-type endopeptidase activity. Acts upstream of or within mammary gland involution; proteolysis; and receptor catabolic process. Located in cytosol; lysosome; and mitochondrion. Is expressed in molar; oral region epithelium; and skin. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 76. Orthologous to human CAPN1 (calpain 1). [provided by Alliance of Genome Resources, Apr 2022]

Capn1 基因产物(2)

mRNA Protein Name
NM_001110504.1 NP_001103974.1 calpain-1 catalytic subunit
NM_007600.3 NP_031626.1 calpain-1 catalytic subunit
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium-dependent cysteine-type endopeptidase activity IDA
IDA: 通过直接分析推断
17529984 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
17529984 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within mammary gland involution IMP
IMP: 通过突变表型推断
22555453 MGI
acts upstream of or within proteolysis IMP
IMP: 通过突变表型推断
22555453 MGI
acts upstream of or within receptor catabolic process IDA
IDA: 通过直接分析推断
17529984 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cornified envelope IDA
IDA: 通过直接分析推断
26644517 MGI
located in cytosol IDA
IDA: 通过直接分析推断
22555453 MGI
located in lysosome IDA
IDA: 通过直接分析推断
22555453 MGI
located in mitochondrion IDA
IDA: 通过直接分析推断
22555453 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

calpain-1 catalytic subunit

CANP 1

calcium-activated neutral proteinase 1

calpain mu-type

calpain-1 large subunit

micromolar-calpain

mu-calpain

muCANP

重组 Capn1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72114 CAPN1 Protein, Mouse (His) O35350 (M1-A713) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Capn1 NCBI NCBI:823