1. Gene
  2. Cd80 - CD80 antigen Gene

Cd80 - CD80 antigen Gene

种属: Mus musculus

同用名: B71; Ly53; TSA1; Cd28l; Ly-53; MIC17

基因 ID: 12519 | 基因类型: protein coding

关于 Cd80

功能概要

Predicted to enable coreceptor activity. Acts upstream of or within T cell costimulation; cellular response to lipopolysaccharide; and positive regulation of alpha-beta T cell proliferation. Located in external side of plasma membrane. Is expressed in heart ventricle and skin. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human CD80 (CD80 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd80 基因产物(2)

mRNA Protein Name
NM_001359898.1 NP_001346827.1 T-lymphocyte activation antigen CD80 precursor
NM_009855.2 NP_033985.3 T-lymphocyte activation antigen CD80 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
1385153 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within T cell costimulation IDA
IDA: 通过直接分析推断
1385153 MGI
acts upstream of or within cellular response to lipopolysaccharide IDA
IDA: 通过直接分析推断
19047410 MGI
acts upstream of or within positive regulation of T cell proliferation IGI
IGI: 通过遗传相互作用推断
23793062 MGI
acts upstream of or within positive regulation of alpha-beta T cell proliferation IDA
IDA: 通过直接分析推断
1385153 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
1385153 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

T-lymphocyte activation antigen CD80

B7 protein

activation B7-1 antigen

重组 Cd80 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7632 B7-1/CD80 Protein, Mouse (HEK293, Fc) Q00609 (V38-K245) ≥95%
HY-P7633 B7-1/CD80 Protein, Mouse (HEK293, His) Q00609 (V38-N246) ≥95%
HY-P77523 B7-1/CD80 Protein, Mouse (Biotinylated, HEK293, His) Q00609 (V38-K245) ≥95%

Cd80 抗体

目录号 产品名 应用 反应物种
HY-P83711m Armenian Hamster Anti-Mouse CD80 Antibody (PE) FC Mouse

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cd80 NCBI NCBI:941
Macaca fascicularis Cd80 NCBI NCBI:102140078
Leporidae Cd80 NCBI
Rattus norvegicus Cd80 NCBI NCBI:25408
Macaca mulatta Cd80 NCBI NCBI:732518