1. Gene
  2. Cirbp - cold inducible RNA binding protein Gene

Cirbp - cold inducible RNA binding protein Gene

种属: Mus musculus

同用名: Cirp

基因 ID: 12696 | 基因类型: protein coding

关于 Cirbp

功能概要

Enables poly(U) RNA binding activity and translation repressor activity. Involved in stress granule assembly. Acts upstream of or within cellular response to cold; negative regulation of cell growth; and regulation of cell cycle G1/S phase transition. Located in cytoplasmic stress granule and nucleoplasm. Is expressed in several structures, including brain and retina. Orthologous to human CIRBP (cold inducible RNA binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Cirbp 基因产物(6)

mRNA Protein Name
NM_001379421.1 NP_001366350.1 cold-inducible RNA-binding protein isoform 2
NM_001379422.1 NP_001366351.1 cold-inducible RNA-binding protein isoform 1
NM_001379423.1 NP_001366352.1 cold-inducible RNA-binding protein isoform 3
NM_001379424.1 NP_001366353.1 cold-inducible RNA-binding protein isoform 1
NM_001379425.1 NP_001366354.1 cold-inducible RNA-binding protein isoform 1
NM_007705.3 NP_031731.1 cold-inducible RNA-binding protein isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA binding IDA
IDA: 通过直接分析推断
9151692 MGI
enables poly(U) RNA binding IDA
IDA: 通过直接分析推断
9151692 MGI
enables translation repressor activity IDA
IDA: 通过直接分析推断
17967451 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to cold IDA
IDA: 通过直接分析推断
9151692 MGI
acts upstream of or within negative regulation of cell growth IMP
IMP: 通过突变表型推断
9151692 MGI
acts upstream of or within regulation of cell cycle G1/S phase transition IDA
IDA: 通过直接分析推断
9151692 MGI
involved in stress granule assembly IDA
IDA: 通过直接分析推断
17967451 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
17967451 MGI
located in cytoplasmic stress granule IDA
IDA: 通过直接分析推断
17967451 MGI
located in nucleoplasm IDA
IDA: 通过直接分析推断
9151692 MGI
located in nucleus IDA
IDA: 通过直接分析推断
17967451 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

cold-inducible RNA-binding protein

A18 hnRNP

glycine-rich RNA-binding protein CIRP

重组 Cirbp 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72145 CIRBP Protein, Mouse (His) P60824 (M1-E172) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cirbp NCBI NCBI:1153