2. Gene
  3. Socs3 - suppressor of cytokine signaling 3 Gene

Socs3 - suppressor of cytokine signaling 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Cis3; Ef10; Ssi3; Cish3; EF-10; SSI-3

基因 ID: 12702 | 基因类型: protein coding

关于 Socs3

功能概要

Enables phosphotyrosine residue binding activity. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; negative regulation of Insulin Receptor signaling pathway; and placenta development. Predicted to be located in cytoplasm. Predicted to be part of phosphatidylinositol 3-kinase complex. Is expressed in several structures, including extraembryonic component; liver; placenta; retina; and spleen. Human ortholog(s) of this gene implicated in atopic dermatitis 4. Orthologous to human SOCS3 (suppressor of cytokine signaling 3). [provided by Alliance of Genome Resources, Apr 2022]

Socs3 基因产物(1)

mRNA Protein Name
NM_007707.3 NP_031733.1 suppressor of cytokine signaling 3
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables miRNA binding IDA
IDA: 通过直接分析推断
30294880 MGI
enables miRNA binding IMP
IMP: 通过突变表型推断
30294880 MGI
enables phosphotyrosine residue binding IMP
IMP: 通过突变表型推断
16302975 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15169905 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within branching involved in labyrinthine layer morphogenesis IMP
IMP: 通过突变表型推断
11481489 MGI
acts upstream of cell differentiation IDA
IDA: 通过直接分析推断
15358627 MGI
acts upstream of cell differentiation IGI
IGI: 通过遗传相互作用推断
15358627 MGI
involved in cellular response to interleukin-17 IDA
IDA: 通过直接分析推断
30294880 MGI
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: 通过表达模式推断
20439489 MGI
acts upstream of or within negative regulation of inflammatory response IGI
IGI: 通过遗传相互作用推断
20530874 MGI
acts upstream of or within negative regulation of insulin receptor signaling pathway IDA
IDA: 通过直接分析推断
15169905 MGI
acts upstream of or within negative regulation of signal transduction IGI
IGI: 通过遗传相互作用推断
15358627 MGI
acts upstream of or within placenta blood vessel development IMP
IMP: 通过突变表型推断
11481489 MGI
acts upstream of or within positive regulation of cell differentiation IDA
IDA: 通过直接分析推断
15358627 MGI
acts upstream of or within positive regulation of cell differentiation IGI
IGI: 通过遗传相互作用推断
15358627 MGI
acts upstream of or within regulation of protein phosphorylation IDA
IDA: 通过直接分析推断
15169905 MGI
acts upstream of signal transduction IGI
IGI: 通过遗传相互作用推断
15358627 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

suppressor of cytokine signaling 3

CIS-3

E2a-Pbx1 target gene in fibroblasts 10

STAT-induced STAT inhibitor 3

cytokine inducible SH2-containing protein 3

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-155335 FPR2 agonist 3 Agonist 99.39% 否
HY-169908 STAT3-IN-37 Inhibitor / 否
HY-RS13554 SOCS3 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS16260 Socs3 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Socs3 NCBI NCBI:9021
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