1. Gene
  2. Ccr8 - chemokine (C-C motif) receptor 8 Gene

Ccr8 - chemokine (C-C motif) receptor 8 Gene

中文名称:趋化因子 (CC 基序) 受体 8

种属: Mus musculus

同用名: C-C; CCR-8; CKR-8; mCCR8; Cmkbr8; CC-CKR-8; C-C CKR-8

基因 ID: 12776 | 基因类型: protein coding

关于 Ccr8

Chromosome 9: 119,921,180-119,923,972 forward strand.GRCm39:CM001002.3

This gene has 1 transcript (splice variant), 236 orthologues, 25 paralogues and is associated with 7 phenotypes. Biased expression in thymus adult (RPKM 6.3), mammary gland adult (RPKM 1.1) and 3 other tissues.

功能概要

该基因编码的蛋白可启动 CC 趋化因子受体活性。在趋化性上游或趋化性内起作用。预测位于质膜中。预计是膜的组成部分。预计在质膜外侧活跃。在中枢神经系统中表达;视网膜;和胸腺原基。与人 CCR8(CC 基序趋化因子受体 8)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables C-C Chemokine Receptor activity. Acts upstream of or within chemotaxis. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in external side of plasma membrane. Is expressed in central nervous system; retina; and thymus primordium. Orthologous to human CCR8 (C-C motif Chemokine Receptor 8). [provided by Alliance of Genome Resources, Apr 2022]

Ccr8 基因产物(1)

mRNA Protein Name
NM_007720.2 NP_031746.1 C-C chemokine receptor type 8
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables C-C chemokine receptor activity IDA
IDA: 通过直接分析推断
9670926 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9670926 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within chemotaxis IDA
IDA: 通过直接分析推断
9670926 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Ccr8 蛋白结构

7tmA_CCR8

7tmA_CCR8: cd15187 (33 - 308)

7tmA_CCR8

7tmA_CCR8: cd15187 (33 - 60)

7tmA_CCR8

7tmA_CCR8: cd15187 (67 - 92)

7tmA_CCR8

7tmA_CCR8: cd15187 (103 - 133)

7tmA_CCR8

7tmA_CCR8: cd15187 (145 - 167)

7tmA_CCR8

7tmA_CCR8: cd15187 (192 - 221)

7tmA_CCR8

7tmA_CCR8: cd15187 (228 - 258)

7tmA_CCR8

7tmA_CCR8: cd15187 (276 - 301)

  • 0
  • 100
  • 200
  • 300
  • 353 a.a.
蛋白主名 其他名称

C-C chemokine receptor type 8

C-C motif chemokine receptor 8

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ccr8 NCBI NCBI:1237
Macaca fascicularis Ccr8 NCBI NCBI:102132857