1. Gene
  2. Cnr2 - cannabinoid receptor 2 (macrophage) Gene

Cnr2 - cannabinoid receptor 2 (macrophage) Gene

中文名称:大麻素受体 2 (巨噬细胞)

种属: Mus musculus

同用名: CB2; CB-2; CB2-R

基因 ID: 12802 | 基因类型: protein coding

关于 Cnr2

Chromosome 4: 135,622,705-135,647,518 forward strand.GRCm39:CM000997.3

This gene has 2 transcripts (splice variants), 196 orthologues, 18 paralogues and is associated with 18 phenotypes. Biased expression in spleen adult (RPKM 19.7), mammary gland adult (RPKM 6.) and 6 other tissues.

功能概要

预测该基因编码的蛋白编码的蛋白可启动大麻素受体活性。作用于白细胞趋化性的上游或内部。预测位于树突中;内质网;和神经细胞体。预测为质膜细胞质侧的外在成分。预计在细胞质和质膜中有活性。以多种结构表达,包括消化系统;中枢神经系统;泌尿生殖系统;免疫系统;以及肝脏和胆道系统。与人类 CNR2(大麻素受体 2)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable Cannabinoid Receptor activity. Acts upstream of or within leukocyte chemotaxis. Predicted to be located in dendrite; endoplasmic reticulum; and neuronal cell body. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Predicted to be active in cytoplasm and plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; immune system; and liver and biliary system. Orthologous to human CNR2 (Cannabinoid Receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Cnr2 基因产物(2)

mRNA Protein Name
NM_009924.4 NP_034054.3 cannabinoid receptor 2
NM_001305278.1 NP_001292207.1 cannabinoid receptor 2
基因本体论
  • 生物过程
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Cnr2 蛋白结构

7tmA_CB2

7tmA_CB2: cd15341 (33 - 309)

7tmA_CB2

7tmA_CB2: cd15341 (34 - 60)

7tmA_CB2

7tmA_CB2: cd15341 (68 - 93)

7tmA_CB2

7tmA_CB2: cd15341 (105 - 135)

7tmA_CB2

7tmA_CB2: cd15341 (147 - 167)

7tmA_CB2

7tmA_CB2: cd15341 (185 - 214)

7tmA_CB2

7tmA_CB2: cd15341 (237 - 267)

7tmA_CB2

7tmA_CB2: cd15341 (277 - 302)

  • 0
  • 100
  • 200
  • 300
  • 347 a.a.
蛋白主名 其他名称

cannabinoid receptor 2

cannabinoid receptor 2 (spleen)

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cnr2 NCBI NCBI:1269