2. Gene
  3. Col18a1 - collagen, type XVIII, alpha 1 Gene

Col18a1 - collagen, type XVIII, alpha 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 12822 | 基因类型: protein coding

关于 Col18a1

功能概要

Predicted to enable identical protein binding activity. Predicted to be an extracellular matrix structural constituent. Acts upstream of or within several processes, including angiogenesis; endothelial cell morphogenesis; and positive regulation of endothelial cell apoptotic process. Located in basement membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Used to study pigment dispersion syndrome. Human ortholog(s) of this gene implicated in primary angle-closure glaucoma. Orthologous to human COL18A1 (collagen type XVIII alpha 1 chain). [provided by Alliance of Genome Resources, Apr 2022]

Col18a1 基因产物(8)

mRNA Protein Name
NM_001109991.2 NP_001103461.1 collagen alpha-1(XVIII) chain isoform 1 precursor
NM_001406250.1 NP_001393179.1 collagen alpha-1(XVIII) chain isoform 3 precursor
NM_001406251.1 NP_001393180.1 collagen alpha-1(XVIII) chain isoform 4 precursor
NM_001406252.1 NP_001393181.1 collagen alpha-1(XVIII) chain isoform 5
NM_001406253.1 NP_001393182.1 collagen alpha-1(XVIII) chain isoform 5
NM_001406254.1 NP_001393183.1 collagen alpha-1(XVIII) chain isoform 5
NM_001406255.1 NP_001393184.1 collagen alpha-1(XVIII) chain isoform 6
NM_009929.4 NP_034059.2 collagen alpha-1(XVIII) chain isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17324935 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within angiogenesis IDA
IDA: 通过直接分析推断
15188432 MGI
acts upstream of or within angiogenesis IMP
IMP: 通过突变表型推断
11927538 MGI
acts upstream of blood vessel endothelial cell migration IDA
IDA: 通过直接分析推断
15188432 MGI
acts upstream of endothelial cell apoptotic process IDA
IDA: 通过直接分析推断
15188432 MGI
acts upstream of or within endothelial cell morphogenesis IDA
IDA: 通过直接分析推断
15188432 MGI
acts upstream of or within extracellular matrix organization IMP
IMP: 通过突变表型推断
15254016 MGI
acts upstream of or within positive regulation of blood vessel endothelial cell migration IDA
IDA: 通过直接分析推断
15188432 MGI
acts upstream of or within positive regulation of endothelial cell apoptotic process IDA
IDA: 通过直接分析推断
15188432 MGI
acts upstream of or within positive regulation of vascular endothelial cell proliferation IDA
IDA: 通过直接分析推断
15188432 MGI
acts upstream of vascular endothelial cell proliferation IDA
IDA: 通过直接分析推断
15188432 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basement membrane IDA
IDA: 通过直接分析推断
7568013 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

collagen alpha-1(XVIII) chain

alpha-1(XVIII) collagen

endostatin

procollagen, type XVIII, alpha 1

重组 Col18a1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70347 Collagen alpha-1(XVIII) chain/COL18A1 Protein, Mouse (HEK293, His) P39061 (H1591-K1774) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02968 COL18A1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Col18a1 NCBI NCBI:80781
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