2. Gene
  3. Cr2 - complement receptor 2 Gene

Cr2 - complement receptor 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Cr1; C3DR; CD21; CD35; Cr-1; Cr-2

基因 ID: 12902 | 基因类型: protein coding

关于 Cr2

功能概要

Enables Complement Receptor activity. Acts upstream of or within with a negative effect on complement activation, alternative pathway. Acts upstream of or within several processes, including cellular response to lipopolysaccharide; immunoglobulin mediated immune response; and skeletal system development. Located in external side of plasma membrane. Human ortholog(s) of this gene implicated in common variable immunodeficiency; nasopharynx carcinoma; and systemic lupus erythematosus. Orthologous to human CR2 (complement C3d receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Cr2 基因产物(2)

mRNA Protein Name
NM_001368765.1 NP_001355694.1 complement receptor type 2 isoform 1 precursor
NM_007758.3 NP_031784.1 complement receptor type 2 isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables complement receptor activity IMP
IMP: 通过突变表型推断
11728339 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11728339 MGI
enables signaling receptor activity IDA
IDA: 通过直接分析推断
11728339 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within bone development IGI
IGI: 通过遗传相互作用推断
19828624 MGI
acts upstream of or within cartilage development IGI
IGI: 通过遗传相互作用推断
19828624 MGI
acts upstream of or within cellular response to lipopolysaccharide IGI
IGI: 通过遗传相互作用推断
19828624 MGI
acts upstream of or within negative effect complement activation, alternative pathway IGI
IGI: 通过遗传相互作用推断
19828624 MGI
acts upstream of or within immunoglobulin mediated immune response IGI
IGI: 通过遗传相互作用推断
19828624 MGI
acts upstream of or within inflammatory response IGI
IGI: 通过遗传相互作用推断
19828624 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
8041705 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

complement receptor type 2

complement C3d receptor

complement receptor type 1

expressed in B lymphocytes

重组 Cr2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77602 CD21 Protein, Mouse (HEK293, His) P19070 (I12-W963) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N12760 Lobophorin CR-2 / 否
HY-NP137 NP-PE (Phycoerythrin) / 否
HY-RS03133 CR2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cr2 NCBI NCBI:1380
Macaca fascicularis Cr2 NCBI NCBI:102145559
Macaca mulatta Cr2 NCBI NCBI:714202
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