2. Gene
  3. Dhh - desert hedgehog Gene

Dhh - desert hedgehog Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 13363 | 基因类型: protein coding

关于 Dhh

功能概要

Enables patched binding activity. Acts upstream of or within several processes, including Leydig cell differentiation; male sex determination; and osteoblast differentiation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including gonad; gut; heart and pericardium; nervous system; and yolk sac. Used to study 46,XY sex reversal. Human ortholog(s) of this gene implicated in 46,XY sex reversal and 46,XY sex reversal 7. Orthologous to human DHH (desert Hedgehog signaling molecule). [provided by Alliance of Genome Resources, Apr 2022]

Dhh 基因产物(1)

mRNA Protein Name
NM_007857.5 NP_031883.1 desert hedgehog protein preproprotein
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables patched binding IPI
IPI: 通过物理相互作用推断
9811851 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10050855 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within Leydig cell differentiation IGI
IGI: 通过遗传相互作用推断
17495005 MGI
acts upstream of or within Leydig cell differentiation IMP
IMP: 通过突变表型推断
12050120 MGI
involved in Schwann cell development IMP
IMP: 通过突变表型推断
10482238 MGI
involved in male gonad development IMP
IMP: 通过突变表型推断
8805249 MGI
acts upstream of or within male sex determination IGI
IGI: 通过遗传相互作用推断
17495005 MGI
acts upstream of or within osteoblast differentiation IDA
IDA: 通过直接分析推断
25639508 MGI
involved in paracrine signaling IMP
IMP: 通过突变表型推断
32151560 MGI
acts upstream of or within regulation of steroid biosynthetic process IGI
IGI: 通过遗传相互作用推断
17495005 MGI
acts upstream of or within smoothened signaling pathway IDA
IDA: 通过直接分析推断
25639508 MGI
acts upstream of or within spermatid development IMP
IMP: 通过突变表型推断
17495005 MGI
involved in spermatogenesis IMP
IMP: 通过突变表型推断
8805249 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

desert hedgehog protein

HHG-3

重组 Dhh 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7339 DHH Protein, Mouse Q61488 (C23-G198, C23I) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03733 DHH Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dhh NCBI NCBI:50846
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