2. Gene
  3. Dlk1 - delta like non-canonical Notch ligand 1 Gene

Dlk1 - delta like non-canonical Notch ligand 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: FA1; ZOG; pG2; DlkI; Peg9; SCP1; DLK-1; Ly107; pref-1

基因 ID: 13386 | 基因类型: protein coding

关于 Dlk1

功能概要

Predicted to enable calcium ion binding activity. Involved in negative regulation of fat cell differentiation and negative regulation of vascular endothelial cell proliferation. Acts upstream of or within several processes, including bone mineralization; negative regulation of Notch signaling pathway; and positive regulation of bone resorption. Located in external side of plasma membrane. Is expressed in several structures, including alimentary system; branchial arch; embryo mesenchyme; genitourinary system; and nervous system. Orthologous to human DLK1 (delta like non-canonical Notch ligand 1). [provided by Alliance of Genome Resources, Apr 2022]

Dlk1 基因产物(4)

mRNA Protein Name
NM_001190703.1 NP_001177632.1 protein delta homolog 1 isoform 2 precursor
NM_001190704.1 NP_001177633.1 protein delta homolog 1 isoform 3 precursor
NM_001190705.1 NP_001177634.1 protein delta homolog 1 isoform 4 precursor
NM_010052.5 NP_034182.2 protein delta homolog 1 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
24928897 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within bone mineralization IMP
IMP: 通过突变表型推断
21308776 MGI
acts upstream of or within embryo development IDA
IDA: 通过直接分析推断
19247431 MGI
acts upstream of or within embryonic skeletal system development IDA
IDA: 通过直接分析推断
19247431 MGI
acts upstream of or within multicellular organism growth IMP
IMP: 通过突变表型推断
21308776 MGI
acts upstream of or within negative regulation of Notch signaling pathway IGI
IGI: 通过遗传相互作用推断
21419176 MGI
involved in negative regulation of fat cell differentiation IDA
IDA: 通过直接分析推断
8500166 MGI
involved in negative regulation of vascular endothelial cell proliferation IDA
IDA: 通过直接分析推断
24584117 MGI
acts upstream of or within ossification IMP
IMP: 通过突变表型推断
21308776 MGI
acts upstream of or within osteoblast differentiation IMP
IMP: 通过突变表型推断
21308776 MGI
acts upstream of or within positive regulation of bone resorption IMP
IMP: 通过突变表型推断
21308776 MGI
acts upstream of or within positive regulation of cytokine production IDA
IDA: 通过直接分析推断
21308776 MGI
acts upstream of or within post-embryonic development IDA
IDA: 通过直接分析推断
19247431 MGI
acts upstream of or within regulation of gene expression IMP
IMP: 通过突变表型推断
19515692 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
18988804 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein delta homolog 1

adipocyte differentiation inhibitor protein

delta-like 1 homolog

fetal antigen 1

preadipocyte factor 1

stromal cell derived protein 1

重组 Dlk1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77915 DLK-1 Protein, Mouse (HEK293, His) Q09163-1 (A24-Q305) ≥95%

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P990613 LIV-1205 (CBA-1205) / Phase 1
Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-114332 GNE-8505 Inhibitor 99.86% 否
HY-RS03806 DLK1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dlk1 NCBI NCBI:8788
Macaca fascicularis Dlk1 NCBI NCBI:102120804
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