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  2. POU5F2 - POU domain class 5, transcription factor 2 Gene

POU5F2 - POU domain class 5, transcription factor 2 Gene

中文名称:POU 域类别 5,转录因子 2

种属: Homo sapiens

同用名: SPRM-1

基因 ID: 134187 | 基因类型: protein coding

关于 POU5F2

This gene has 1 transcript (splice variant), 511 orthologues and 17 paralogues.

功能概要

预测可实现 DNA 结合转录因子活性、RNA 聚合酶 II 特异性和 RNA 聚合酶 II 顺式调节区序列特异性 DNA 结合活性。预计参与 RNA 聚合酶 II 的转录调控。预测位于核内。预测是染色质的一部分。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of chromatin. [provided by Alliance of Genome Resources, Apr 2022]

POU5F2 基因产物(1)

mRNA Protein Name
NM_153216.2 NP_694948.1 POU domain, class 5, transcription factor 2

POU5F2 蛋白结构

Pou

Pou: Pou domain - N-terminal to homeobox domain (123 - 192)

Homeobox

Homeobox: Homeobox domain (223 - 261)

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  • 328 a.a.
蛋白主名 其他名称

POU domain, class 5, transcription factor 2

sperm 1 POU domain transcription factor

关联疾病

疾病名称 别名
Bosch-Boonstra-Schaaf Optic Atrophy Syndrome

BBSOAS

Optic Atrophy-Intellectual Disability Syndrome

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus POU5F2 MGD MGI:1922757
Rattus norvegicus POU5F2 RGD RGD:1589456