2. Gene
  3. CPA2 - carboxypeptidase A2 Gene

CPA2 - carboxypeptidase A2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：羧肽酶 A2

种属: Homo sapiens

基因 ID: 1358 | 基因类型: protein coding

关于 CPA2

Cytogenetic location: 7q32.2 Genomic coordinates (GRCh38): 7:130,266,863-130,289,798 (from NCBI)

This gene has 4 transcripts (splice variants), 197 orthologues and 8 paralogues. Restricted expression toward pancreas (RPKM 5496.0).

功能概要

已分离出三种不同形式的人胰原羧肽酶 A。编码的蛋白质代表 A2 形式，它是一种单体蛋白质，具有与 A1 和 A3 形式不同的生化特性。 A2 形式的胰原羧肽酶作用于芳香族 C 末端残基，是一种分泌蛋白。[RefSeq 提供，2008 年 12 月]

Three different forms of human pancreatic procarboxypeptidase A have been isolated. The encoded protein represents the A2 form, which is a monomeric protein with different biochemical properties from the A1 and A3 forms. The A2 form of pancreatic procarboxypeptidase acts on aromatic C-terminal residues and is a secreted protein. [provided by RefSeq, Dec 2008]

CPA2 基因产物(1)

mRNA Protein Name
NM_001869.3 NP_001860.2 carboxypeptidase A2 precursor
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables carboxypeptidase activity IDA
IDA: 通过直接分析推断
2920728 GOA
enables metallocarboxypeptidase activity IDA
IDA: 通过直接分析推断
2920728 GOA
enables zinc ion binding IDA
IDA: 通过直接分析推断
2920728 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular region IDA
IDA: 通过直接分析推断
2920728 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CPA2 蛋白结构

Propep_M14

Propep_M14: Carboxypeptidase activation peptide (29 - 103)

Peptidase_M14

Peptidase_M14: Zinc carboxypeptidase (130 - 405)

  • 0
  • 100
  • 200
  • 300
  • 419 a.a.
蛋白主名 其他名称

carboxypeptidase A2

carboxypeptidase A2 (pancreatic)

重组 CPA2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7733 Carboxypeptidase A2/CPA2 Protein, Human (HEK293, His) AAP36067.1 (L17-Y417) ≥95%

CPA2 抗体

目录号 产品名 应用 反应物种
HY-P82741 Carboxypeptidase A1/A2/B Antibody (YA2486) WB, IHC-P, ICC/IF Human, Mouse, Rat

关联疾病

疾病名称 别名
Myasthenic Syndrome, Congenital, 10

Congenital Myasthenic Syndrome 10

CMS10

Lgm

Myasthenia, Limb-Girdle, Familial

Myasthenia, Limb-Girdle, Familial, Formerly

Lgm, Formerly

Congenital Myasthenic Syndrome Type Ib, Formerly

Cms1b, Formerly

Cms Ib, Formerly

Myasthenic Myopathy, Formerly

Familial Limb-Girdle Myasthenia

Cms1b

Cms Ib

Congenital Myasthenic Syndrome Type 1b

Congenital Myasthenic Syndrome Type Ib

Myasthenic Myopathy

Myasthenic Syndrome, Congenital, Type 10

Congenital Myasthenic Syndrome Ib

Myopathy In Myasthenia Gravis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03081 CPA2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus CPA2 VGNC VGNC:61112
Macaca mulatta CPA2 VGNC VGNC:108393
Rattus norvegicus CPA2 RGD RGD:1305563
Mus musculus CPA2 MGD MGI:3617840
Others CPA2 NCBI
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