1. Gene
  2. Ephb4 - Eph receptor B4 Gene

Ephb4 - Eph receptor B4 Gene

种属: Mus musculus

同用名: Htk; MDK2; Myk1; Tyro11; b2b2412Clo

基因 ID: 13846 | 基因类型: protein coding

关于 Ephb4

功能概要

Predicted to enable transmembrane-ephrin receptor activity. Involved in angiogenesis; Ephrin Receptor signaling pathway; and heart morphogenesis. Acts upstream of or within positive regulation of T cell costimulation; positive regulation of aorta morphogenesis; and venous blood vessel morphogenesis. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in neuron projection. Predicted to be integral component of plasma membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and sensory organ. Used to study cystic kidney disease. Human ortholog(s) of this gene implicated in hereditary lymphedema. Orthologous to human EphB4 (EPH receptor B4). [provided by Alliance of Genome Resources, Apr 2022]

Ephb4 基因产物(2)

mRNA Protein Name
NM_001159571.1 NP_001153043.1 ephrin type-B receptor 4 isoform a precursor
NM_010144.6 NP_034274.4 ephrin type-B receptor 4 isoform b precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12971893 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in angiogenesis IMP
IMP: 通过突变表型推断
10518221 MGI
involved in ephrin receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
10518221 MGI
involved in heart morphogenesis IMP
IMP: 通过突变表型推断
10518221 MGI
acts upstream of or within positive regulation of T cell costimulation IGI
IGI: 通过遗传相互作用推断
15599401 MGI
acts upstream of or within positive regulation of aorta morphogenesis IMP
IMP: 通过突变表型推断
18952909 MGI
acts upstream of or within venous blood vessel morphogenesis IMP
IMP: 通过突变表型推断
18952909 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

ephrin type-B receptor 4

developmental kinase 2

hepatoma transmembrane kinase

mDK-2

tyrosine kinase MYK-1

重组 Ephb4 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73004 EphB4 Protein, Mouse (HEK293, Fc) P54761 (L16-A539) ≥95%
HY-P73005 EphB4 Protein, Mouse (HEK293, His) P54761 (L16-A539) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ephb4 NCBI NCBI:2050