2. Gene
  3. TAF1L - TATA-box binding protein associated factor 1 like Gene

TAF1L - TATA-box binding protein associated factor 1 like Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：TATA 盒结合蛋白相关因子 1 样

种属: Homo sapiens

同用名: TAF2A2; TAF(II)210

基因 ID: 138474 | 基因类型: protein coding

关于 TAF1L

Cytogenetic location: 9p21.1 Genomic coordinates (GRCh38): 9:32,629,454-32,635,669 (from NCBI)

This gene has 1 transcript (splice variant), 200 orthologues and 1 paralogue.

功能概要

该基因座是无内含子的，显然是在灵长类动物谱系中从 X 染色体上的多外显子 TAF1 基因座的转录物逆转录转座而来的。该基因在雄性生殖细胞中表达，该产品已被证明可与 TAF1 产品互换使用。[RefSeq 提供，2015 年 8 月]

This locus is intronless, and apparently arose in the primate lineage from retrotransposition of the transcript from the multi-exon TAF1 locus on the X chromosome. The gene is expressed in male germ cells, and the product has been shown to function interchangeably with the TAF1 product. [provided by RefSeq, Aug 2015]

TAF1L 基因产物(1)

mRNA Protein Name
NM_153809.2 NP_722516.1 transcription initiation factor TFIID subunit 1-like
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables TBP-class protein binding IPI
IPI: 通过物理相互作用推断
12217962 GOA
enables lysine-acetylated histone binding IDA
IDA: 通过直接分析推断
22464331 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in male meiotic nuclear division IEP
IEP: 通过表达模式推断
12217962 GOA
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
12217962 GOA
involved in regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
12217962 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TAF1L 蛋白结构

TBP-binding

TBP-binding: TATA box-binding protein binding (21 - 85)

DUF3591

DUF3591: Protein of unknown function (DUF3591) (584 - 1046)

zf-CCHC_6

zf-CCHC_6: Zinc knuckle (1280 - 1319)

Bromodomain

Bromodomain: Bromodomain (1409 - 1488)

Bromodomain

Bromodomain: Bromodomain (1532 - 1614)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1500
  • 1826 a.a.
蛋白主名 其他名称

transcription initiation factor TFIID subunit 1-like

TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like

关联疾病

疾病名称 别名
Dystonia 3, Torsion, X-Linked

X-Linked Dystonia-Parkinsonism

DYT3

Xdp

Lubag

Dystonia-Parkinsonism, X-Linked

Torsion Dystonia-Parkinsonism, Filipino Type

Dyt-Taf1

X-Linked Dystonia-Parkinsonism Syndrome

X-Linked Torsion Dystonia-Parkinsonism Syndrome

Dystonia Musculorum Deformans

X-Linked Dystonia-Parkinsonism/Lubag

Lubag Syndrome

Dystonia-3

Torsion Dystonia-Parkinsonism Filipino Type

X-Linked Torsion Dystonia 3

Dystonia, Torsion, X-Linked, Type 3
Dystonia 12

DYT12

Rdp

Generalized Dystonia

Dystonia-12

Rapid-Onset Dystonia-Parkinsonism

Familial Dystonia

Dystonia Musculorum Deformans

Dystonic Disorders

Idiopathic Familial Dystonia

Dystonia-Parkinsonism, Rapid-Onset

Fragments Of Torsion Dystonia

Dyt-Atp1a3

Rapid-Onset Dystonia Parkinsonism

Rodp

Dystonia, Type 12

Dystonia 3, Torsion, X-Linked

Idiopathic Non-Familial Dystonia

Symptomatic Torsion Dystonia

Dystonia Disorders
Focal Dystonia

Dystonia, Focal, Task-Specific
Segmental Dystonia
Dystonia 1, Torsion, Autosomal Dominant

Dystonia Musculorum Deformans 1

Dystonia Musculorum Deformans

DYT1

Early-Onset Torsion Dystonia

Eotd

Dystonia-1, Torsion

Torsion Dystonia 1

Autosomal Dominant Torsion Dystonia 1

Dystonia-1

Oppenheim'S Dystonia

Oppenheim-Ziehen Disease

Early Onset Torsion Dystonia

Dystonia 3, Torsion, X-Linked
Cervical Dystonia

Spasmodic Torticollis
Dystonia, Dopa-Responsive

Dystonia 5

Dopa-Responsive Dystonia

DRD

Dyt5

Dystonia-Parkinsonism With Diurnal Fluctuation

Dyt-Th

Hpd With Diurnal Fluctuation

Hereditary Progressive Dystonia With Diurnal Fluctuation

Dystonia, Progressive, With Diurnal Variation

Segawa Syndrome, Autosomal Dominant

Dystonia, Dopa-Responsive, Autosomal Dominant

Dopa-Responsive Dystonia, Autosomal Dominant

Dystonia, Dopa-Responsive, With Or Without Hyperphenylalaninemia

Dyt-Gch1

Dyt-Spr

Dystonia 5, Dopa-Responsive Type

Hereditary Progressive Dystonia With Marked Diurnal Fluctuation

Autosomal Dominant Dopa-Responsive Dystonia

Autosomal Dominant Segawa Syndrome

Dystonia-5

Progressive Dystonia With Diurnal Fluctuation

Dystonia, Type 5, Dopa-Responsive Type
Spasmodic Dystonia

Laryngeal Dystonia
Hemidystonia
Multifocal Dystonia
Blepharospasm
Lymphatic Malformation 5

Meige Syndrome

Meige Disease

Meige Lymphedema

Lymphedema Praecox

Lymphedema, Late-Onset

Late-Onset Lymphedema

LMPH2

Meigs Syndrome

LMPHM5

Lymphedema, Hereditary, Ii, Formerly

Lmph2, Formerly

Hereditary Lymphedema Ii

Demons-Meigs Syndrome

Hereditary Lymphedema Type Ii

Lymphedema, Hereditary, 2

Lymphedema, Hereditary, Ii

Meige'S Disease
Oromandibular Dystonia
Alternating Hemiplegia Of Childhood

Alternating Hemiplegia

Ahc

Alternating Hemiplegia Syndrome

Hemiplegia, Alternating, Of Childhood

Hemiplegia, Crossed
Movement Disease

Movement Disorders

Movement Disorder
Parkinson Disease, Late-Onset

Parkinson Disease

Parkinson'S Disease

PD

PARK

Parkinson Disease, Susceptibility To

Late Onset Parkinson'S Disease

Late Onset Parkinson Disease

Paralysis Agitans

Primary Parkinsonism

Idiopathic Parkinson Disease

Parkinson'S

Parkinson Disease, Late-Onset, Susceptibility To

Parkinson Disease, Age Of Onset, Modifier

Lewy Body Parkinson Disease

Idiopathic Parkinson'S Disease

Pd - [Parkinson Disease]

Parkinson Disease Nos

Parkinson, Nos

Primary Parkinson Disease
Dystonia

Dystonic Disease

Dystonic Disorder

Dystonia Disorders

Neuroleptic Dyskinesia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-107424 BAY-299 Inhibitor 99.40% 否
HY-RS14166 TAF1L Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus TAF1L MGD MGI:1336878
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